Thinning of the retinal nerve fiber and choroidal layers in adolescents with anorexia nervosa: A controlled study.

IF 1.1 4区医学 Q3 OPHTHALMOLOGY

Arquivos brasileiros de oftalmologia Pub Date : 2024-04-19 eCollection Date: 2024-01-01 DOI:10.5935/0004-2749.2023-0047

Ceyda Baskan, Alkım Oden Akman, Elif Akcay, Sabite Emine Gökce, Demet Tas

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引用次数: 0

Abstract

Purpose: We aimed to evaluate retinal nerve fiber and choroidal layer alterations in adolescents with anorexia nervosa using spectral-domain optical coherence tomography.

Methods: Thirty patients with anorexia nervosa and 30 healthy adolescents aged 12-18 years were included in this study. Their age, sex, body mass index, anorexia nervosa type, disease duration, and spectral-domain optical coherence tomography data were recorded.

Results: Central macular thickness and retinal nerve fiber layer thickness in the temporal and inferior regions were significantly lesser in patients with anorexia than in healthy controls (p<0.05). Moreover, significant choroidal thinning around the foveal and subfoveal regions in patients with anorexia was observed (p<0.05). In addition, a statistically significant relation between the increase in disease duration and the thinning of the inferior retinal nerve fiber layer was detected (p<0.05).

Conclusion: The retinal nerve fiber layer and choroidal layer thicknesses were lesser in patients with anorexia than in healthy controls. Screening for retinal indices might prevent the development of irreversible retinal pathologies in adolescents with anorexia nervosa. In addition, thinning of the retinal nerve fiber and choroidal layers could reflect structural or functional changes in the brain of adolescents with anorexia nervosa.

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神经性厌食症青少年视网膜神经纤维层和脉络膜层变薄：对照研究

目的：我们旨在使用光谱域光学相干断层扫描评估神经性厌食症青少年视网膜神经纤维和脉络膜层的改变：研究对象包括 30 名神经性厌食症患者和 30 名 12-18 岁的健康青少年。记录他们的年龄、性别、体重指数、神经性厌食症类型、病程和光谱域光学相干断层扫描数据：结果：厌食症患者的黄斑中心厚度和颞部及下部视网膜神经纤维层厚度明显低于健康对照组（p）：厌食症患者的视网膜神经纤维层和脉络膜层厚度低于健康对照组。筛查视网膜指数可预防神经性厌食症青少年出现不可逆的视网膜病变。此外，视网膜神经纤维层和脉络膜层变薄可能反映了神经性厌食症青少年大脑结构或功能的变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arquivos brasileiros de oftalmologia OPHTHALMOLOGY-

CiteScore

1.60

自引率

0.00%

发文量

200

审稿时长

6-12 weeks

期刊介绍： The ABO-ARQUIVOS BRASILEIROS DE OFTALMOLOGIA (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - electronic version), the official bimonthly publication of the Brazilian Council of Ophthalmology (CBO), aims to disseminate scientific studies in Ophthalmology, Visual Science and Health public, by promoting research, improvement and updating of professionals related to the field.