Computerized clinical decision support to improve stroke prevention therapy in primary care management of atrial fibrillation: a cluster randomized trial

IF 3.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Jafna Cox , Laura Hamilton , Lehana Thabane , Gary Foster , James MacKillop , Feng Xie , Antonio Ciaccia , Shurjeel Choudhri , Joanna Nemis-White , Ratika Parkash , IMPACT-AF Investigators
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引用次数: 0

Abstract

Background

Despite guidelines supporting antithrombotic therapy use in atrial fibrillation (AF), under-prescribing persists. We assessed whether computerized clinical decision support (CDS) would enable guideline-based antithrombotic therapy for AF patients in primary care.

Methods

This cluster randomized trial of CDS versus usual care (UC) recruited participants from primary care practices across Nova Scotia, following them for 12 months. The CDS tool calculated bleeding and stroke risk scores and provided recommendations for using oral anticoagulants (OAC) per Canadian guidelines.

Results

From June 14, 2014 to December 15, 2016, 203 primary care providers (99 UC, 104 CDS) with access to high-speed Internet were recruited, enrolling 1,145 eligible patients (543 UC, 590 CDS) assigned to the same treatment arm as their provider. Patient mean age was 72.3 years; most were male (350, 64.5% UC, 351, 59.5% CDS) and from a rural area (298, 54.9% UC, 315, 53.4% CDS). At baseline, a higher than anticipated proportion of patients were receiving guideline-based OAC therapy (373, 68.7% UC, 442, 74.9% CDS; relative risk [RR] 0.97 (95% confidence interval [CI], 0.87-1.07; P = .511)). At 12 months, prescription data were available for 538 usual care and 570 CDS patients, and significantly more CDS patients were managed according to guidelines (415, 77.1% UC, 479, 84.0% CDS; RR 1.08 (95% CI, 1.01-1.15; P = .024)).

Conclusion

Notwithstanding high baseline rates, primary care provider access to the CDS over 12 months further optimized the prescribing of OAC therapy per national guidelines to AF patients potentially eligible to receive it. This suggests that CDS can be effective in improving clinical process of care.

Trial Registration

Clinical Trials NCT01927367. https://clinicaltrials.gov/ct2/show/NCT01927367?term=NCT01927367&draw=2&rank=1

计算机化临床决策支持改善心房颤动初级医疗管理中的卒中预防治疗:分组随机试验
背景:尽管指南支持心房颤动(房颤)患者使用抗血栓治疗,但处方不足的情况依然存在。我们评估了计算机化临床决策支持(CDS)是否能在初级医疗中为房颤患者提供基于指南的抗血栓治疗:这项计算机临床决策支持(CDS)与常规护理(UC)的分组随机试验从新斯科舍省的初级保健实践中招募参与者,并对他们进行为期 12 个月的跟踪。CDS工具计算出血和中风风险评分,并根据加拿大指南提供使用口服抗凝药(OAC)的建议:从 2014 年 6 月 14 日至 2016 年 12 月 15 日,共招募了 203 家可接入高速互联网的初级医疗服务提供商(99 家 UC,104 家 CDS),招募了 1145 名符合条件的患者(543 名 UC,590 名 CDS),将他们分配到与其提供商相同的治疗组。患者的平均年龄为 72.3 岁;大多数为男性(350 人,64.5% UC;351 人,59.5% CDS),来自农村地区(298 人,54.9% UC;315 人,53.4% CDS)。基线时,接受基于指南的 OAC 治疗的患者比例高于预期(373 例,68.7% UC,442 例,74.9% CDS;相对风险 [RR] 0.97(95% 置信区间 [CI],0.87-1.07;P=0.511))。12个月后,538名常规护理患者和570名CDS患者的处方数据可用,根据指南管理的CDS患者明显更多(415名,77.1% UC,479名,84.0% CDS;RR 1.08 (95% CI, 1.01-1.15; p=0.024)):尽管基线比例较高,但初级医疗服务提供者在 12 个月内使用 CDS 进一步优化了根据国家指南向可能符合接受 OAC 治疗的房颤患者开具处方的情况。这表明,CDS能有效改善临床护理流程:Clinical Trials NCT01927367. https://clinicaltrials.gov/ct2/show/NCT01927367?term=NCT01927367&draw=2&rank=1.
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
American heart journal
American heart journal 医学-心血管系统
CiteScore
8.20
自引率
2.10%
发文量
214
审稿时长
38 days
期刊介绍: The American Heart Journal will consider for publication suitable articles on topics pertaining to the broad discipline of cardiovascular disease. Our goal is to provide the reader primary investigation, scholarly review, and opinion concerning the practice of cardiovascular medicine. We especially encourage submission of 3 types of reports that are not frequently seen in cardiovascular journals: negative clinical studies, reports on study designs, and studies involving the organization of medical care. The Journal does not accept individual case reports or original articles involving bench laboratory or animal research.
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