MSD: Continuous Pharmaceutical Manufacturing Data for the 2024 MSOM Data-Driven Research Challenge

Manufacturing & Service Operations Management Pub Date : 2024-04-29 DOI:10.1287/msom.2024.0860

Tugce Martagan, Marc Baaijens, Coen Dirckx, James Holman, Robert Meyer, Oscar Repping, Bram van Ravenstein

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Abstract

To support the 2024 MSOM Data-Driven Research Challenge, Merck & Co., Inc., Rahway, New Jersey (hereafter “MSD”), provides pharmaceutical manufacturing data from a continuous tablet production setting. The data set contains approximately 300 million data points related to around 75 process parameters monitored over 120 hours. In this paper, we present the data set and share our vision to inspire and facilitate new applications of operations management (OM) methodologies in pharmaceutical manufacturing. We begin with an introduction to pharmaceutical manufacturing for OM researchers and then elaborate on emerging technologies, common industry challenges, and research opportunities. We explain the data set and propose a roadmap for future research directions. Researchers are welcome to examine the proposed research questions or analyze other research questions using the data set.History: This paper has been accepted as part of the 2024 MSOM Data-Driven Research Challenge.Funding: This work was supported by The Dutch Research Council - NWO VIDI Grant.Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2024.0860

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MSD：为 2024 年 MSOM 数据驱动研究挑战提供连续的制药数据

为支持 2024 MSOM 数据驱动研究挑战赛，位于新泽西州拉威的默克公司（以下简称 "MSD"）提供了来自连续片剂生产环境的制药生产数据。数据集包含约 3 亿个数据点，涉及 120 小时内监控的约 75 个过程参数。在本文中，我们将介绍该数据集，并分享我们的愿景，以启发和促进运营管理 (OM) 方法在制药业中的新应用。我们首先为运营管理研究人员介绍了医药制造，然后详细阐述了新兴技术、常见行业挑战和研究机会。我们解释了数据集，并提出了未来研究方向的路线图。欢迎研究人员使用该数据集研究提出的研究问题或分析其他研究问题：本文已作为 2024 年 MSOM 数据驱动研究挑战赛的一部分被接受：这项工作得到了荷兰研究理事会--NWO VIDI 基金的支持：在线附录见 https://doi.org/10.1287/msom.2024.0860

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Manufacturing & Service Operations Management

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