A Comprehensive Review on Synthesis of Thiazoles: Research on Magnetically Recoverable Catalysts

Abstract

In chemistry, thiazoles and their derivatives constitute a significant class of biologically active molecules that are thought to be the fundamental building blocks of numerous other biologically active compounds. Many synthetic pharmaceuticals, including fungicides, dyes, antimicrobials, and anticonvulsants, are made using thiazoles and their derivatives as an intermediary. Thus, one of the main areas of organic synthesis research is the presentation of effective and environmentally acceptable catalytic methods for the synthesis of thiazole derivatives. Over the past ten years, organic synthesis in chemistry has been completely transformed by the use of magnetic nanocomposites as catalysts. Magnetic nanoparticles are very stable and easily manipulated on the surface, which can result in the creation of an efficient catalyst. The main feature of magnetic nanocatalysts is their ability to be easily separated from the reaction mixture using only an external magnet. In recent years, several magnetic nanocatalysts have been reported to produce various thiazole compounds. We will look at these methods and talk about the characteristics of these catalytic systems in this post. This review will be helpful for synthetic chemists who are interested in magnetic nanocatalysts and working in the field of thiazole synthesis.