Valorization of guabirobeira leaf extracts (Campomanesia xanthocarpa) through pressurized liquid extraction and aqueous infusion: assessment of phytochemical composition, antibacterial, and antioxidant activities

IF 2.8 4区生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Journal of chemical technology and biotechnology Pub Date : 2024-04-26 DOI:10.1002/jctb.7663

Lucíola Bagatini, Bruno Fischer, Giovana Paula Zandoná, Liziane Schittler Moroni, Alexander Junges, Aniela Pinto Kempka, Cesar Valmor Rombaldi

{"title":"Valorization of guabirobeira leaf extracts (Campomanesia xanthocarpa) through pressurized liquid extraction and aqueous infusion: assessment of phytochemical composition, antibacterial, and antioxidant activities","authors":"Lucíola Bagatini, Bruno Fischer, Giovana Paula Zandoná, Liziane Schittler Moroni, Alexander Junges, Aniela Pinto Kempka, Cesar Valmor Rombaldi","doi":"10.1002/jctb.7663","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> BACKGROUND</h3>\n \n <p>The leaves of guabirobeira contain important phenolic and flavonoid compounds, known for their antioxidant, anti-inflammatory, antibacterial, and antinociceptive activities. The purpose of this work was to obtain extracts from guabirobeira leaves through aqueous infusion and pressurized liquid extraction with water, ethanol, and a combination of water–ethanol (ratio 1:1, v/v; PLE-W:E). Subsequently, we used liquid chromatography coupled with mass spectrometry to identify the chemical compounds, and to study the antioxidant activity in rat brain cells; thiobarbituric acid reactive substances (TBARS) and reactive oxygen species (ROS) antibacterial activity against Gram-negative and Gram-positive bacteria were also seen.</p>\n </section>\n \n <section>\n \n <h3> RESULTS</h3>\n \n <p>According to the findings, all four extracts contained a significant amount of phytochemical compounds. Among them, the PLE-W:E extract showed a higher concentration of flavonoids, demonstrating significant antioxidant activity in <i>in vitro</i> assays of TBARS and ROS in rat brain cells. It also exhibited antibacterial activity against both Gram-positive and Gram-negative bacteria.</p>\n </section>\n \n <section>\n \n <h3> CONCLUSION</h3>\n \n <p>Guabirobeira leaf extracts hold promise as a potential source of bioactive compounds. These extracts can be applied across various sectors, including cosmetics and skincare products, pharmaceuticals, food and beverages, natural preservatives, and functional materials. By exploring these potential applications, valuable contributions can be made to the field of sustainable chemistry and pharmacy, furthering the utilization of guabirobeira leaf extracts in diverse industries. This approach also aligns with the promotion of environmentally friendly and sustainable practices. © 2024 Society of Chemical Industry (SCI).</p>\n </section>\n </div>","PeriodicalId":15335,"journal":{"name":"Journal of chemical technology and biotechnology","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chemical technology and biotechnology","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jctb.7663","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

BACKGROUND

The leaves of guabirobeira contain important phenolic and flavonoid compounds, known for their antioxidant, anti-inflammatory, antibacterial, and antinociceptive activities. The purpose of this work was to obtain extracts from guabirobeira leaves through aqueous infusion and pressurized liquid extraction with water, ethanol, and a combination of water–ethanol (ratio 1:1, v/v; PLE-W:E). Subsequently, we used liquid chromatography coupled with mass spectrometry to identify the chemical compounds, and to study the antioxidant activity in rat brain cells; thiobarbituric acid reactive substances (TBARS) and reactive oxygen species (ROS) antibacterial activity against Gram-negative and Gram-positive bacteria were also seen.

RESULTS

According to the findings, all four extracts contained a significant amount of phytochemical compounds. Among them, the PLE-W:E extract showed a higher concentration of flavonoids, demonstrating significant antioxidant activity in in vitro assays of TBARS and ROS in rat brain cells. It also exhibited antibacterial activity against both Gram-positive and Gram-negative bacteria.

CONCLUSION

Guabirobeira leaf extracts hold promise as a potential source of bioactive compounds. These extracts can be applied across various sectors, including cosmetics and skincare products, pharmaceuticals, food and beverages, natural preservatives, and functional materials. By exploring these potential applications, valuable contributions can be made to the field of sustainable chemistry and pharmacy, furthering the utilization of guabirobeira leaf extracts in diverse industries. This approach also aligns with the promotion of environmentally friendly and sustainable practices. © 2024 Society of Chemical Industry (SCI).

查看原文本刊更多论文

通过加压液体萃取和水浸法对瓜比罗贝拉叶提取物（Campomanesia xanthocarpa）进行估值：评估植物化学成分、抗菌和抗氧化活性

背景瓜子叶含有重要的酚类和类黄酮化合物，具有抗氧化、抗炎、抗菌和抗痛觉活性。这项研究的目的是通过水浸法（AI）和加压液体萃取法（PLE-W）、乙醇萃取法（PLE-E）以及水与乙醇比例为 1:1 v/v 的组合萃取法（PLE-W:E）从瓜叶菊叶片中提取提取物。随后，利用液相色谱法结合质谱法对化合物进行鉴定，并研究了大鼠脑细胞的抗氧化活性、硫代巴比妥酸活性物质（TBARS）和活性氧（ROS）对革兰氏阴性菌和革兰氏阳性菌的抗菌活性。其中，PLE-W:E 提取物中黄酮类化合物的浓度较高，在大鼠脑细胞 TBARS 和 ROS 体外检测中表现出显著的抗氧化活性。此外，它还对两种细菌（革兰氏阳性菌和革兰氏阴性菌）具有抗菌活性。这些提取物可应用于各个领域，包括化妆品和护肤品、药品、食品和饮料、天然防腐剂和功能材料。通过探索这些潜在的应用领域，可以为可持续化学和制药领域做出宝贵的贡献，促进瓜子黄杨叶提取物在不同行业中的应用。这种方法也符合促进环境友好和可持续发展的做法。本文受版权保护。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of chemical technology and biotechnology 工程技术-工程：化工

CiteScore

7.00

自引率

5.90%

发文量

268

审稿时长

1.7 months

期刊介绍： Journal of Chemical Technology and Biotechnology(JCTB) is an international, inter-disciplinary peer-reviewed journal concerned with the application of scientific discoveries and advancements in chemical and biological technology that aim towards economically and environmentally sustainable industrial processes.