Osiris gene family defines the cuticle nanopatterns of Drosophila.

IF 3.3 3区生物学

Genetics Pub Date : 2024-04-23 DOI:10.1093/genetics/iyae065

Zhengkuan Sun, Sachi Inagaki, Keita Miyoshi, Kuniaki Saito, Shigeo Hayashi

引用次数: 0

Abstract

Nanostructures of pores and protrusions in the insect cuticle modify molecular permeability and surface wetting, and help insects sense various environmental cues. However, the cellular mechanisms that modify cuticle nanostructures are poorly understood. Here, we elucidate how insect-specific Osiris family genes are expressed in various cuticle-secreting cells in the Drosophila head during the early stages of cuticle secretion and cover nearly the entire surface of the head epidermis. Furthermore, we demonstrate how each sense organ cell with various cuticular nanostructures expressed a unique combination of Osiris genes. Osiris gene mutations cause various cuticle defects in the corneal nipples and pores of the chemosensory sensilla. Thus, our study emphasizes on the importance of Osiris genes for elucidating cuticle nanopatterning in insects.

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Osiris 基因家族确定了果蝇角质层的纳米形态。

昆虫角质层中的纳米孔隙和突起结构可改变分子渗透性和表面润湿性，并帮助昆虫感知各种环境线索。然而，人们对改变角质层纳米结构的细胞机制知之甚少。在这里，我们阐明了昆虫特异性 Osiris 家族基因如何在果蝇头部分泌角质层的早期阶段在各种分泌角质层的细胞中表达，并覆盖头部表皮的几乎整个表面。此外，我们还展示了具有各种角质层纳米结构的每个感觉器官细胞是如何表达独特的 Osiris 基因组合的。Osiris 基因突变会导致角膜乳头和化学感觉器孔的各种角质层缺陷。因此，我们的研究强调了 Osiris 基因对于阐明昆虫角质层纳米结构的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Genetics 生物-遗传学

CiteScore

6.20

自引率

6.10%

发文量

177

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