A. Ciobanu, V. Plesca, S. Doltu, M. Manea, L. Domente, A. Dadu
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引用次数: 0
Abstract
SETTINGThe Republic of Moldova, one of Europe's poorest countries, also bears one of the highest burdens of rifampicin-resistant TB (RR-TB).OBJECTIVESTo trace the patients’
journey through TB in terms of the relationship with poverty and assess its determinants.DESIGNThis cross-sectional study used secondary data from a survey assessing catastrophic costs in RR-TB-affected households.RESULTSData were obtained from 430 RR-TB patients. The percentage of poor TB-affected households rose from 65% prior to TB to 86% after TB treatment completion (P < 0.001). Social factors leading to poverty were identified for each stage:
diagnostic period (history of incarceration: cOR 2.3, 95% CI 1.1–5.2); treatment period (being unemployed or unofficially employed: cOR 6.7, 95% CI 4.3–10.0); and post-treatment (being married or cohabiting: cOR 5.7, 95% CI 2.9–11.0). Participants who had ≥3 members in
their households were more likely to be poor at all TB stages: diagnostic period (cOR 5.7, 95% CI 3.7–8.8), treatment period (cOR 3.8, 95% CI 2.5–5.6) and post-treatment (cOR 7.2, 95% CI 3.6–14.3).CONCLUSIONThe
study identified risk factors associated with poverty at each stage of TB. These findings outline that innovative social protection policies are required to protect TB patients against poverty.
背景摩尔多瓦共和国是欧洲最贫穷的国家之一,同时也是耐利福平肺结核(RR-TB)负担最重的国家之一。目的追踪肺结核患者的治疗过程与贫困的关系,并评估其决定因素。受肺结核影响的贫困家庭比例从肺结核前的 65% 上升到肺结核治疗结束后的 86%(P < 0.001)。导致贫困的社会因素在每个阶段都有所体现:诊断期(监禁史:cOR 2.3,95% CI 1.1-5.2);治疗期(失业或非正式就业:cOR 6.7,95% CI 4.3-10.0);治疗后(已婚或同居:cOR 5.7,95% CI 2.9-11.0)。在所有肺结核阶段:诊断期(cOR 5.7,95% CI 3.7-8.8)、治疗期(cOR 3.8,95% CI 2.5-5.6)和治疗后(cOR 7.2,95% CI 3.6-14.3),家庭成员≥3 人的参与者更有可能处于贫困状态。这些发现表明,需要创新的社会保护政策来保护结核病患者免受贫困的困扰。