Medical and social features of the obstetric and gynecological profile of women who have overcome infertility with the help of ART.

K. Moiseeva, V. K. Yuryev, Sh D Kharbediya, K. G. Shevtsova, A. Alekseeva
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Abstract

To increase the birth rate, in addition to increasing the availability of ART, their high effectiveness is necessary. The effectiveness of providing this type of medical care is influenced by a significant number of medical, social and organizational factors. Achieving a positive result during IVF largely depends on the obstetric history of the expectant mother. Purpose. To determine the medical and social characteristics of the obstetric and gynecological profile of patients at the Center for Reproduction and Family Planning who had a positive result in the treatment of infertility using IVF. Materials and methods. Using a specially developed statistical form “Questionnaire for medical and social examination of women suffering from infertility,” an anonymous survey was conducted of 398 women whose pregnancy resulted from the IVF procedure. The significance of differences in indicators was assessed using Student’s t-test. Differences were considered significant at p<0,05. Statistical data processing was carried out using the MS Office‑2016 and StatSoft-Statistica 10.0 software packages. Results. With an average age of onset of sexual activity of 18,82± years, sexual debut before 18 years of age was observed in 32,7% of patients. Most often, for the first time, women sought medical help for infertility within 2–5 years after the start of regular sexual activity (65,4%) (m=3,38±0,17 years) to obstetrician-gynecologists at antenatal clinics and planning centers families (83,0%). Despite the fact that the average age of initial diagnosis of infertility was 28,86±0,34 years, 38,2% of women were diagnosed with infertility after 30 years of age, and 55.3% of all requests for medical help for problems with conception came from private medical organizations. In most cases, before being referred for IVF, women underwent treatment at antenatal clinics and family planning centers (91,3%). The obstetric and gynecological profile of women who have overcome infertility with the help of ART is characterized by: a history of negative IVF results (50.4%), absence of children before this pregnancy (87,0%), low detection of gynecological diseases in childhood (13,1%) and the presence of abortions (27,1%). 38,9% of patients who had a history of pregnancy terminations had two or more abortions (m=1,61±0,03 abortions). In the study group, a high frequency of abortions for medical reasons and spontaneous terminations of pregnancy was revealed (31,5% and 24,1%, respectively). Conclusion. The established obstetric and gynecological profile of women who have overcome infertility with the help of ART has revealed a significant number of medical and social risk factors, which makes it possible to develop organizational measures aimed at improving the provision of medical care to this group of women.
在抗逆转录病毒疗法帮助下克服不孕症的妇女的妇产科医学和社会特征。
要提高出生率,除了增加抗逆转录病毒疗法的可用性外,还必须提高其有效性。提供这类医疗服务的有效性受到大量医疗、社会和组织因素的影响。在试管婴儿过程中能否取得积极的结果,在很大程度上取决于准妈妈的产科病史。目的确定生殖和计划生育中心利用试管婴儿治疗不孕症取得阳性结果的患者妇产科概况的医学和社会特征。材料和方法使用专门编制的统计表格 "不孕症妇女医疗和社会检查问卷",对 398 名通过试管婴儿手术怀孕的妇女进行了匿名调查。指标差异的显著性采用学生 t 检验法进行评估。P<0.05为差异显著。统计数据的处理使用 MS Office-2016 和 StatSoft-Statistica 10.0 软件包。结果开始性活动的平均年龄为(18.82±)岁,32.7%的患者在 18 岁前初次性行为。最常见的情况是,妇女在开始有规律的性活动后 2-5 年内(65.4%)(m=3.38±0.17 岁)首次因不孕症向产前诊所和计划生育中心的妇产科医生求助(83.0%)。尽管初次诊断不孕症的平均年龄为(28.86±0.34)岁,但有 38.2%的妇女在 30 岁以后才被确诊为不孕症,而且在所有因受孕问题寻求医疗帮助的请求中,有 55.3%来自私人医疗机构。在大多数情况下,妇女在接受体外受精之前,都在产前诊所和计划生育中心接受过治疗(91.3%)。在抗逆转录病毒疗法帮助下克服了不孕症的妇女的妇产科特征为:试管婴儿结果为阴性 (50.4%),怀孕前无子女(87.0%),儿童时期妇科疾病检出率低(13.1%),曾流产(27.1%)。38.9%有过终止妊娠史的患者有过两次或两次以上的人工流产(m=1.61±0.03)。在研究组中,因医疗原因流产和自然终止妊娠的频率很高(分别为 31.5%和 24.1%)。结论在抗逆转录病毒疗法帮助下克服了不孕症的妇女的妇产科概况显示,她们存在大量的医疗和社会风险因素,因此有可能制定组织措施,改善为这一妇女群体提供的医疗服务。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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