Transversus Abdominis Plane Block versus Epidural Anesthesia for Pain Management Post-Caesarean Delivery: A Pilot Study

J. Salazar-Flórez, Leidy Arenas-Cardona, Ninemy Marhx, Eduardo López-Guerrero, Ángela Echeverri-Rendón, Luz Giraldo-Cardona
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Abstract

Background Effective post-operative analgesia profoundly influences patient recovery and outcomes after caesarean delivery. The Transversus Abdominis Plane (TAP) block represents a potential alternative, potentially offering greater effectiveness than epidural analgesia while causing fewer adverse effects. Objective To assess if the abdominal transverse block provides superior postoperative pain relief in patients undergoing caesarean delivery compared to epidural analgesia. Methods Participants were divided into parallel groups: an experimental group receiving TAP block (n=25) and a control group receiving epidural analgesia (n=24). All patients received a 10 mg dose of hyoscine at the end of the surgery. Experimental Group received a total of 20 mL of 0.2% ropivacaine. In Epidural group received 0.2% ropivacaine at 4 mL/h for 24 hours. All participants were administered combined with neuroaxial block anesthesia. The patients selected for epidural analgesia received the mentioned dose, while the other group block had the epidural catheter removed after the cesarean section. The primary outcome was post-caesarean pain, evaluated using the Visual Analog Scale (VAS) at four intervals (0, 6, 12, and 24 hours). Also, surgical bleeding and residual motor were evaluated. VAS pain scores between the groups were compared using the Friedman test and Generalized Linear Model (GLM) for non-normally distributed data. The effect size was estimated with Eta Square (\documentclass[12pt]{minimal} \usepackage{wasysym} \usepackage[substack]{amsmath} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage[mathscr]{eucal} \usepackage{mathrsfs} \DeclareFontFamily{T1}{linotext}{} \DeclareFontShape{T1}{linotext}{m}{n} {linotext }{} \DeclareSymbolFont{linotext}{T1}{linotext}{m}{n} \DeclareSymbolFontAlphabet{\mathLINOTEXT}{linotext} \begin{document} ${\eta ^2}$\end{document}), considering values ≥0.38 as indicative of large effects. A two-tailed p-value < 0.05 was deemed statistically significant. Results Statistically significant differences in pain scores were noted at 0 and 6 hours post-surgery (p<0.01). The TAP block group reported lower pain scores at 0 hours (mean=0.04) and 6 hours (mean=1.16) compared to the epidural group, reflecting a substantial effect size. Conclusion The TAP block proves advantageous in mitigating postoperative pain for women post-caesarean delivery, particularly in the initial 6 postpartum hours. This relief promotes early mother-infant bonding and facilitates breastfeeding.
腹横肌平面阻滞与硬膜外麻醉用于剖腹产后疼痛控制:一项试点研究
背景 有效的术后镇痛对剖腹产后患者的恢复和预后有着深远的影响。腹横肌平面 (TAP) 阻滞是一种潜在的替代方法,可能比硬膜外镇痛更有效,同时不良反应更少。目的 评估腹横肌阻滞与硬膜外镇痛相比是否能更好地缓解剖腹产患者的术后疼痛。方法 将参与者分为两组:实验组接受 TAP 阻滞(25 人),对照组接受硬膜外镇痛(24 人)。所有患者均在手术结束时接受 10 毫克剂量的东莨菪碱。实验组总共使用了 20 毫升 0.2% 罗哌卡因。硬膜外组接受 0.2% 罗哌卡因,剂量为 4 毫升/小时,持续 24 小时。所有参与者都接受了神经轴阻滞麻醉。选择硬膜外镇痛的患者接受上述剂量,而另一组阻滞患者则在剖宫产术后拔除硬膜外导管。主要结果是剖腹产后疼痛,使用视觉模拟量表(VAS)在四个时间间隔(0、6、12 和 24 小时)进行评估。此外,还对手术出血量和残余运动量进行了评估。采用弗里德曼检验和非正态分布数据的广义线性模型(GLM)比较各组间的 VAS 疼痛评分。效应大小用 Eta Square(\documentclass[12pt]{minimal})估计。\usepackage{wasysym}\usepackage[substack]{amsmath}\usepackage{amsfonts} (我们的软件包{amsfonts})。\usepackage{amssymb}\usepackage{amsbsy} \usepackage[mathscr]{eucal} \usepackage{mathrsfs}\DeclareFontFamily{T1}{linotext}{}\DeclareFontShape{T1}{linotext}{m}{n}{linotext }{}\DeclareSymbolFont{linotext}{T1}{linotext}{m}{n} {linotext }{}\DeclareSymbolFontAlphabet{\mathLINOTEXT}{linotext }{}\开始{document}${\eta ^2}$\end{document}),认为值≥0.38 表示有较大影响。双尾 p 值小于 0.05 即为具有统计学意义。结果 手术后 0 小时和 6 小时的疼痛评分差异有统计学意义(P<0.01)。与硬膜外麻醉组相比,TAP阻滞组在 0 小时(平均值=0.04)和 6 小时(平均值=1.16)时的疼痛评分较低,反映出显著的效应大小。结论 TAP 阻滞在减轻剖宫产术后妇女的术后疼痛方面具有优势,尤其是在产后最初的 6 小时内。这种疼痛的缓解促进了母婴关系的早日建立,并有利于母乳喂养。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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