A randomized control trial investigating the effectiveness of a commercial pneumonia vaccine (Part II): Weaned lambs

IF 1.6 3区 农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE
M.D. Gardner , J. Van Donkersgoed , C.A. Bauman , M.T. Spinato
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Abstract

The objective of this randomized controlled vaccine field trial was to determine the effectiveness of a commercial respiratory bacterin, Ovipast™ Plus, administered to feedlot lambs at weaning, approximately 8 wk of age, to improve animal health, growth performance, and carcass traits. Lambs were weaned, weighed, and sorted into groups by sex and the previous Ovipast™ Plus vaccination status of their mother, because this is stage 2 of that ongoing trial (Gardner et al., 2023). Lambs born to vaccinated ewes were vaccinated with the Ovipast™ Plus bacterin and revaccinated 3–5 wk later. Lambs born to unvaccinated ewes were not vaccinated. During the growing and finishing phases of the trial, vaccination did not reduce pneumonia treatment rates, crude or pneumonia specific mortality rates, or improve growth rates. Vaccinated lambs had a lower carcass fat cover (P < 0.001) and a 1.33 times increased odds of yielding a Grade 1 carcass compared to unvaccinated lambs (P = 0.01). Vaccination reduced carcass fat cover and improved yield grades, but it had no beneficial effect on disease rates or growth performance, suggesting a limited economic benefit of vaccinating lambs post-weaning, which were borne from ewes vaccinated with Ovipast™ Plus during gestation.

调查商用肺炎疫苗有效性的随机对照试验(第二部分):断奶羔羊
本随机对照疫苗田间试验的目的是确定在饲养场羔羊断奶(约 8 周龄)时接种商业呼吸道细菌素 Ovipast™ Plus 的效果,以改善动物健康、生长性能和胴体性状。羔羊断奶、称重并按性别及其母亲之前的 Ovipast™ Plus 疫苗接种情况分组,因为这是正在进行的试验的第二阶段(Gardner 等人,2023 年)。接种过疫苗的母羊产下的羔羊接种了 Ovipast™ Plus 细菌素,并在 3-5 周后再次接种。未接种疫苗的母羊所产的羔羊不接种疫苗。在试验的生长和育成阶段,接种疫苗并没有降低肺炎治疗率、粗死亡率或肺炎特定死亡率,也没有提高生长率。与未接种疫苗的羔羊相比,接种疫苗的羔羊胴体脂肪覆盖率较低(P < 0.001),胴体1级的几率增加了1.33倍(P = 0.01)。接种疫苗可降低胴体脂肪覆盖率并提高产量等级,但对疾病发生率或生长性能没有益处,这表明断奶后接种疫苗的羔羊经济效益有限,这些羔羊是在妊娠期接种了Ovipast™ Plus疫苗的母羊所产。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Small Ruminant Research
Small Ruminant Research 农林科学-奶制品与动物科学
CiteScore
3.10
自引率
11.10%
发文量
210
审稿时长
12.5 weeks
期刊介绍: Small Ruminant Research publishes original, basic and applied research articles, technical notes, and review articles on research relating to goats, sheep, deer, the New World camelids llama, alpaca, vicuna and guanaco, and the Old World camels. Topics covered include nutrition, physiology, anatomy, genetics, microbiology, ethology, product technology, socio-economics, management, sustainability and environment, veterinary medicine and husbandry engineering.
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