Surface Modification of Ti-6Al-4V Alloy by Polycaprolactone-Graphene Oxide Composite Coating

Abstract

In this research, Polycaprolactone-graphene oxide Nanocomposite coating was synthesized and characterized by Electrospinning on Ti6AL4V alloy. In order to create a uniform coating with optimal thickness, the effective parameters of Electrospinning coating, including solvent, polymer concentration, and bioceramic percentage, were investigated. Also, the cytotoxicity and corrosion tests were evaluated by the electrochemical polarization test method of the created coating in comparisons and different percentages. In order to characterize the coating, a test such as a scanning electron microscope was used. The results showed that as much as the amount of Graphene oxide is increased, the diameter of Nanofibers decreases. The diameter of Polycaprolactone Nanofibers was 1.3 micrometers, which increases to 56.0 micrometers by adding Graphene oxide. The results of the corrosion test showed that the use of Nano composite coating increased the corrosion resistance to the size of the coating. The nanocomposite coating consists of polycaprolactone nanofibers and graphene oxide, which mimics the behavior of the extracellular matrix and improves the biological and antibacterial behavior of the titanium surface. So far, there has been no report on the creation of this fibrous nanocomposite coating on titanium. The results of the cytotoxicity test showed that the use of Nanocomposite coating has effectively reduced the cytotoxicity on the scaffolds. By creating a polycaprolactone-graphene oxide nanofiber composite coating, the biological and antibacterial properties of titanium alloy will be improved and its corrosion resistance will probably change. In this project, the main question is extracting effective parameters in creating a composite coating on titanium surface by electrospinning method and characterizing and biological evaluation of the created coating.