Comparison of pain control between lignocaine and prilocaine spray versus oral analgesia in post-circumcision patients: a prospective randomized controlled trial in a tertiary care center

Manu K. Nagabhairava, Abhishek Kulkarni, Ameya R. Sangle, Tarun Javali, Mani C. Reddy, Sandeep P.
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Abstract

Background: Pain in the postoperative period is of particular concern. It is a major barrier in the uptake of circumcision. There are various systemic and local analgesics for the management of postoperative pain. However, data regarding efficacy is scarce. Therefore, the present pilot study was conducted to compare the efficacy of lidocaine and prilocaine spray with oral analgesics for the relief of pain. Methods: After obtaining ethics approval and written informed consent, 100 patients meeting the inclusion and exclusion criteria were included. After circumcision, patients were randomized into group A (Lidocaine and prilocaine spray) and group B (Oral analgesics). Pain was assessed by visual analogue scale (VAS) score and patient reported comfort levels were assessed in the postoperative period till 72 hours. Findings were noted and analysed. Results: Both the groups were similar in terms of demographic characteristics and baseline characteristics. The VAS score was significantly lower in group A and the patient-reported comfort level was significantly more in group A. Conclusions: We recommend that the lidocaine and prilocaine spray is better in relieving pain in the postoperative period following circumcision as compared to oral analgesics.
比较利多卡因和普鲁卡因喷雾剂与口服镇痛剂对包皮环切术后患者的镇痛效果:在一家三级医疗中心进行的前瞻性随机对照试验
背景:术后疼痛尤其令人担忧。它是包皮环切术的一个主要障碍。有多种全身和局部镇痛药可用于治疗术后疼痛。然而,有关疗效的数据却很少。因此,本试验性研究旨在比较利多卡因和普鲁卡因喷雾剂与口服镇痛药在缓解疼痛方面的疗效:方法:在获得伦理批准和书面知情同意后,纳入 100 名符合纳入和排除标准的患者。包皮环切术后,患者被随机分为A组(利多卡因和普鲁卡因喷雾剂)和B组(口服镇痛剂)。通过视觉模拟量表(VAS)评分对疼痛进行评估,并在术后 72 小时内对患者报告的舒适度进行评估。对结果进行了记录和分析:结果:两组患者的人口统计学特征和基线特征相似。结果:两组的人口统计学特征和基线特征相似,A 组的 VAS 评分明显较低,A 组患者报告的舒适度明显较高:我们建议,与口服镇痛药相比,利多卡因和普鲁卡因喷雾剂能更好地缓解包皮环切术后的疼痛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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