Risk factors for the development of candidemia in patients with positive urine surveillance culture for Candida spp.

Abstract

The objective of the study was to characterize candiduria in patients admitted to a tertiary hospital and establish the risk factors associated with the development of candidemia. To this end, a laboratory and clinical surveillance study was carried out with samples of Candida spp. previously isolated from urine surveillance cultures of patients admitted to the Intensive Care Unit, during the period from 2019 to 2020. It was demonstrated that the incidence of candidemia in patients with positive urine cultures for Candida spp. it was 17.7 per 1000 admissions and 80% of patients who developed candidemia died. The chance of developing candidemia was eight times greater in patients who had diseases of the digestive system that caused hospitalization and 26 times greater in those who had Coronary Artery Disease (CAD), compared to patients who did not have the comorbidity. We concluded that the possibility of developing candidemia from candiduria is 4.5%, however, the onset of candidemia, regardless of the source, worsens the patient's prognosis.