Addition of Intermittent Pneumatic Compression to Conventional Treatment Improves Volume Reduction Before Lymphatic Surgery for Lower Limb Lymphedema: A Pilot Study.

IF 0.7 4区医学 Q4 IMMUNOLOGY

Lymphology Pub Date : 2024-04-14 DOI:10.2458/lymph.6066

C. Campisi, E. Parodi, A. Demoro, R. Risso, W. D. Brinda, C. Campisi

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引用次数: 0

Abstract

This study assesses the impact of an advanced intermittent pneumatic compression device (IPC - Lympha Press® Optimal Plus) when added to Complete Decongestive Therapy (CDT) compared to CDT alone on volume reduction of limbs with lymphedema. The goal is to maximally reduce edema in preparation for microsurgery. Fifty subjects scheduled for Multiple Lymphatic-Venous Anastomosis (MLVA) were randomly (sequentially) assigned to experimental or control group: 25 (21 females and 4 males) in the experimental IPC group and 25 (20 females and 5 males) in the control group. The two groups were similar in age, sex distribution, and type of lymphedema. Results indicate the IPC group reported greater volume loss than the control group (p= 0.00137) comparing final vs. initial limb volume. The average percentage edema volume loss achieved with added IPC was two times greater (11.7%) than in the control group (5.0%). When differences in treatment duration were accounted for, the IPC group achieved consistently greater proportional volume loss (12.83% vs 6.30%) than conservative therapy alone. In our pilot study, IPC added to CDT resulted in greater proportional volume loss and provides better preparation for MLVA surgery.

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在常规治疗的基础上增加间歇性气压疗法可改善下肢淋巴水肿手术前的体积缩小效果：试点研究。

这项研究评估了先进的间歇性气动加压装置（IPC - Lympha Press® Optimal Plus）与单纯的完全缓解充血疗法（CDT）相比，在完全缓解充血疗法中加入间歇性气动加压装置对减少淋巴水肿肢体体积的影响。目的是最大限度地减轻水肿，为显微手术做好准备。计划进行多淋巴管-静脉吻合术（MLVA）的 50 名受试者被随机（按顺序）分配到实验组或对照组：实验组 IPC 25 人（21 名女性和 4 名男性），对照组 IPC 25 人（20 名女性和 5 名男性）。两组的年龄、性别分布和淋巴水肿类型相似。结果表明，对比最终肢体体积和初始肢体体积，IPC 组比对照组的水肿体积减少得更多（P= 0.00137）。添加IPC后，水肿体积减少的平均百分比（11.7%）是对照组（5.0%）的两倍。如果考虑到治疗持续时间的差异，IPC 组的水肿体积减少比例（12.83% vs 6.30%）始终高于单纯的保守疗法。在我们的试点研究中，在 CDT 的基础上加用 IPC 可使体积按比例缩小，为 MLVA 手术做更好的准备。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lymphology 医学-免疫学

CiteScore

5.20

自引率

8.00%

发文量

审稿时长

3 months

期刊介绍： The Journal contains original articles, special features (see below), and information regarding the International Society of Lymphology. It seeks original papers dealing with clinical and basic studies of the lymphatic system and its disorders including related fields. Articles are accepted for external review and publication on the condition that they are contributed to Lymphology only and that no substantial part has been or will be published elsewhere.