Discriminatory resonance energy transfer mediated by a chiral environment

Abstract

In this study, we delve into the crucial influence of and enhancement by chiral environments on the discriminatory capabilities of RET. Firstly, we scrutinize the impact of a macroscopic chiral medium enveloping the interacting molecules; secondly, we probe the effect of a chiral mediating molecule in close proximity to the system. Importantly, our findings demonstrate that chiral environments not only modulate pre-existing discriminatory effects but also introduce novel mechanisms for discrimination. Central to our research is the application of an innovative model for chiral local-field corrections, which unveils a remarkable distance-dependent inversion of the discrimination dynamics. Our study extends beyond the confines of any specific molecular system, offering a comprehensive discussion of these diverse effects, thereby providing insights with broader implications. Finally, we present a comparative analysis across all studied systems, illustrating our insights by employing 3-methyl-cyclopentanone as an example molecule.