Recombinant ACE2 - Opportunities and Challenges in COVID-19 Treatment.

Q3 Pharmacology, Toxicology and Pharmaceutics

Infectious disorders drug targets Pub Date : 2024-04-18 DOI:10.2174/0118715265298816240321045741

Rahul Sandhu, Mandeep Kaur, Akriti Aggarwal

引用次数: 0

Abstract

It was in 2019 that the world experienced the devastation caused by SARS-COV-2, contributing to a large number of deaths. This contagious virus not only challenged the health care system but has also hit the economy very badly. There has been a lot of research on effective vaccine development, and there has been some success in the same, but no effective antiviral drugs are available in the market. No doubt vaccination can prevent the disease, but it doesn't have the potential to cure an infected person, for which there is a dire need to develop some effective drug. Angiotensin convertase enzyme 2 (ACE2) played a substantial role in SARS-COV2 pathogenesis and thus has gained much attention during the pandemic. Moreover, it has opened up new avenues for the cure of COVID-19.

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重组 ACE2 - COVID-19 治疗的机遇与挑战。

就在 2019 年，全世界经历了 SARS-COV-2 带来的灾难，造成大量人员死亡。这种传染性病毒不仅挑战了医疗保健系统，也对经济造成了严重打击。人们对有效疫苗的开发进行了大量研究，并取得了一些成功，但市场上还没有有效的抗病毒药物。毫无疑问，接种疫苗可以预防疾病，但却无法治愈感染者，因此迫切需要开发一些有效的药物。血管紧张素转换酶 2（ACE2）在 SARS-COV2 发病过程中发挥了重要作用，因此在这次大流行中备受关注。此外，它还为治疗 COVID-19 开辟了新的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Infectious disorders drug targets Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

3.10

自引率

0.00%

发文量

123

期刊介绍： Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continues to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.