Myocardial infarction in persons aged ≥75 years: factors influencing inhospital mortality

Abstract

Aim. To identify factors influencing inhospital mortality in patients with myocardial infarction aged ≥75.Material and methods. We performed a retrospective analysis of medical records of all patients aged ≥75 years hospitalized from January 1, 2020 to December 31, 2021 with a diagnosis of myocardial infarction (I21, ICD-10), assessment of comorbidities, clinical performance, laboratory and treatment data and their impact on the outcome of hospitalization.Results. Inhospital mortality was 22,2%. The mean age of discharged and deceased patients was 81 [79; 84] and 82 [79; 85] years, respectively (p=0,12). Cardiogenic shock on admission (hazard ratio (HR) 31,28; 95% confidence interval (CI) 5,7-171,53; p<0,001), degree 2-3 atrioventricular block (HR 4,67; 95% CI 1,02-21,38; p=0,04), as well as a GRACE score ≥166 for non-ST-segment elevation acute coronary syndrome (HR 7,19; 95% CI 1,01-51,43; p<0,001) showed an unfavorable effect on prognosis.Conclusion. Cardiogenic shock, degree 2-3 atrioventricular block, and a GRACE score ≥166 for patients with non-ST-segment elevation acute coronary syndrome are factors that increase inhospital mortality in patients aged ≥75 years.