Risk of Sarcopenia Identified by Sarc-Calf, Nutritional Status and Hand Grip Strength in Patients with Hematological Cancer

Lorraine Pires Avancini, Laís Freitas da Costa, Mariana de Souza Vieira, Vanusa Felício de Souza, Rayne de Almeida Marques, Jose Luiz Marques Rocha, G. Petarli, V. Guandalini
{"title":"Risk of Sarcopenia Identified by Sarc-Calf, Nutritional Status and Hand Grip Strength in Patients with Hematological Cancer","authors":"Lorraine Pires Avancini, Laís Freitas da Costa, Mariana de Souza Vieira, Vanusa Felício de Souza, Rayne de Almeida Marques, Jose Luiz Marques Rocha, G. Petarli, V. Guandalini","doi":"10.18502/ijhoscr.v18i2.15370","DOIUrl":null,"url":null,"abstract":"Background: Hematological cancer patients are prone to the development of sarcopenia and impaired nutritional and functional status. SARC-CalF is a screening tool for the risk of sarcopenia that has shown good results in this population. This study aimed to identify the risk of sarcopenia by SARC-CalF and to verify its association with nutritional status and Hand Grip Strength (HGS) in patients with hematological cancer. \nMaterials and Methods: Adult patients, of both sexes, with hematological cancer, and in outpatient care participated in the study. We measured the Hand Grip Strength of the Dominant Hand (HGSD) and the Adductor Pollicis Muscle Thickness of the Dominant Hand (APMTD). Moreover, we applied the Patient-Generated Subjective Global Assessment (PG-SGA) and SARC-CalF. Data were analyzed with SPSS® software, 22.0, with a significance level of 5.0%. \nResults: Fifty-one patients aged an average of 60.4 ± 15.1 years were evaluated. Of those, 58.8% were elderly, 51% female, and 80.4% declared themselves non-white. The predominant diagnosis was Mature B Lymphoid Cell Neoplasia (37.7%), and 60.8% of the patients had a diagnosis time of ≤ 3 years. PG-SGA revealed that 35.3% of the patients were malnourished; APMTD and HGSD revealed that 60.8% and 25.5% had reduced muscle strength, respectively. SARC-CalF exposed that 39.2% of the patients were at risk for sarcopenia. Significant associations were found between SARC-CalF and diagnosis time ≤ 3 years (p = 0.039), PG-SGA (p = 0.020), APMTD (p = 0.039) and HGSD (p = 0.002). After binary logistic regression adjusted for age and sex, the reduced HGSD remained associated with the risk of sarcopenia. \nConclusion: SARC-CalF identified a risk of sarcopenia in 39.2% of patients. The reduced HGSD was associated with the risk of sarcopenia.","PeriodicalId":94048,"journal":{"name":"International journal of hematology-oncology and stem cell research","volume":"102 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of hematology-oncology and stem cell research","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.18502/ijhoscr.v18i2.15370","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Hematological cancer patients are prone to the development of sarcopenia and impaired nutritional and functional status. SARC-CalF is a screening tool for the risk of sarcopenia that has shown good results in this population. This study aimed to identify the risk of sarcopenia by SARC-CalF and to verify its association with nutritional status and Hand Grip Strength (HGS) in patients with hematological cancer. Materials and Methods: Adult patients, of both sexes, with hematological cancer, and in outpatient care participated in the study. We measured the Hand Grip Strength of the Dominant Hand (HGSD) and the Adductor Pollicis Muscle Thickness of the Dominant Hand (APMTD). Moreover, we applied the Patient-Generated Subjective Global Assessment (PG-SGA) and SARC-CalF. Data were analyzed with SPSS® software, 22.0, with a significance level of 5.0%. Results: Fifty-one patients aged an average of 60.4 ± 15.1 years were evaluated. Of those, 58.8% were elderly, 51% female, and 80.4% declared themselves non-white. The predominant diagnosis was Mature B Lymphoid Cell Neoplasia (37.7%), and 60.8% of the patients had a diagnosis time of ≤ 3 years. PG-SGA revealed that 35.3% of the patients were malnourished; APMTD and HGSD revealed that 60.8% and 25.5% had reduced muscle strength, respectively. SARC-CalF exposed that 39.2% of the patients were at risk for sarcopenia. Significant associations were found between SARC-CalF and diagnosis time ≤ 3 years (p = 0.039), PG-SGA (p = 0.020), APMTD (p = 0.039) and HGSD (p = 0.002). After binary logistic regression adjusted for age and sex, the reduced HGSD remained associated with the risk of sarcopenia. Conclusion: SARC-CalF identified a risk of sarcopenia in 39.2% of patients. The reduced HGSD was associated with the risk of sarcopenia.
通过血液肿瘤患者的 Sarc-Calf、营养状况和手部握力识别肌少症风险
背景:血液肿瘤患者容易出现肌肉疏松症,营养和功能状况也会受损。SARC-CalF 是一种筛查肌肉疏松症风险的工具,在这一人群中显示出良好的效果。本研究旨在通过 SARC-CalF 确定血液肿瘤患者的肌肉疏松症风险,并验证其与营养状况和手握力(HGS)之间的关联。材料与方法:参与研究的患者均为门诊患者,男女不限。我们测量了支配手的握力(HGSD)和支配手的内收肌厚度(APMTD)。此外,我们还采用了患者自发主观全面评估(PG-SGA)和 SARC-CalF。数据采用 SPSS® 软件 22.0 进行分析,显著性水平为 5.0%。结果接受评估的 51 名患者平均年龄为(60.4 ± 15.1)岁。其中 58.8%为老年人,51%为女性,80.4%自称非白人。主要诊断为成熟 B 淋巴细胞瘤(37.7%),60.8%的患者确诊时间不超过 3 年。PG-SGA显示35.3%的患者营养不良;APMTD和HGSD分别显示60.8%和25.5%的患者肌力下降。SARC-CalF 显示 39.2% 的患者有肌少症风险。研究发现,SARC-CalF 与诊断时间≤ 3 年(p = 0.039)、PG-SGA(p = 0.020)、APMTD(p = 0.039)和 HGSD(p = 0.002)之间存在显著关联。在对年龄和性别进行二元逻辑回归调整后,HGSD 的降低仍与肌肉疏松症的风险相关。结论SARC-CalF 确定了 39.2% 的患者存在肌少症风险。HGSD的降低与肌少症的风险有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信