Success predictors of decompressive surgical treatment for lumbar degenerative spinal canal stenosis

A. Krutko, A. G. Nazarenko, G. E. Balychev, E. Baykov, O.I. Leonova
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Abstract

BACKGROUND: Decompressive surgical treatment for degenerative lumbar stenosis significantly improves patient clinical status. However, in some cases, patients are not satisfied with the outcomes. Various studies have examined clinical and morphological factors to improve the results of surgical interventions. AIM: To identify clinical and morphological predictors of the success of decompressive surgical interventions for lumbar degenerative stenosis. MATERIALS AND METHODS: This retrospective study included 61 patients who underwent surgery for mono- and postsegmental lumbar degenerative stenosis. Clinical and demographic data and the stage of degenerative changes in the functional spinal unit and sagittal balance of the spine were assessed. The success of surgical treatment was defined as simultaneous compliance with three criteria after 6–18 months: achievement of MCID for ODI (≥12%), recalibration of the spinal canal at the level of intervention according to MRI data (Schizas regression to ≥1 stage), and improvement of the patient’s subjective feeling (4–5 on the Likert scale). Logistic regression analysis was used to identify predictors of treatment outcome. RESULTS: A significant decrease in the intensity of pain syndrome (VAS in back and leg) and an improvement in the quality of life (ODI) after surgery (p 0.001) were found in all patients. In 73.8% of cases, the MCID threshold exceeded for ODI, whereas in 75.41%, patients were satisfied with surgical treatment. The success rate of surgical intervention was 65.57%. In one-factor regression analysis of clinical, demographic, and morphological parameters, the only independent predictor of surgical treatment was neuropathic pain before surgery according to the DN4 questionnaire (OR=1.52; p=0.011). CONCLUSION: Decompressive surgical treatment for degenerative lumbar stenosis is an effective treatment method, regardless of the extent and degree of degenerative changes in the spinal–motor segments and concomitant degenerative pathology, including disruption of sagittal balance. The predicting factor of the success of decompressive intervention is the severity of preoperative neuropathic pain.
腰椎退行性椎管狭窄症减压手术治疗的成功预测因素
背景:针对退行性腰椎管狭窄症的减压手术治疗可显著改善患者的临床状况。但在某些情况下,患者对治疗效果并不满意。为改善手术治疗效果,多项研究对临床和形态学因素进行了研究。目的:确定腰椎退行性狭窄症减压手术干预成功的临床和形态学预测因素。材料与方法:该回顾性研究纳入了61例接受手术治疗的单节段和后节段腰椎退行性狭窄症患者。评估了临床和人口统计学数据,以及脊柱功能单元和脊柱矢状平衡的退行性变化阶段。手术治疗的成功定义为 6-18 个月后同时符合三个标准:达到 ODI 的 MCID(≥12%)、根据 MRI 数据重新校准干预水平的椎管(Schizas 回归到≥1 期)和患者主观感觉的改善(Likert 量表 4-5)。采用逻辑回归分析确定治疗结果的预测因素。结果:所有患者术后疼痛综合征的强度(腰部和腿部的 VAS)明显降低,生活质量(ODI)明显改善(P 0.001)。在 73.8% 的病例中,ODI 超过了 MCID 临界值,而在 75.41% 的病例中,患者对手术治疗表示满意。手术治疗的成功率为 65.57%。在临床、人口统计学和形态学参数的单因素回归分析中,手术治疗的唯一独立预测因素是根据 DN4 问卷得出的术前神经病理性疼痛(OR=1.52;P=0.011)。结论:无论脊柱运动节段退行性改变的范围和程度以及伴随的退行性病变,包括矢状面平衡的破坏,对退行性腰椎管狭窄症进行减压手术治疗都是一种有效的治疗方法。减压干预成功与否的预测因素是术前神经病理性疼痛的严重程度。
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