Increased rate of pancreatitis in gender diverse and transgender patients on hormone therapy: a case series study

IF 3.3 Q2 GASTROENTEROLOGY & HEPATOLOGY
Alexander Podboy, Catherine Casey, Ross C D Buerlein, Daniel S Strand, Vanessa M Shami, Andrew Y Wang
{"title":"Increased rate of pancreatitis in gender diverse and transgender patients on hormone therapy: a case series study","authors":"Alexander Podboy, Catherine Casey, Ross C D Buerlein, Daniel S Strand, Vanessa M Shami, Andrew Y Wang","doi":"10.1136/bmjgast-2023-001312","DOIUrl":null,"url":null,"abstract":"Background There is limited data on the incidence of gastrointestinal-specific pathology in gender non-conforming (GNC) populations. Methods Retrospective analysis of pancreatitis incidence rates in transgender and GNC persons exposed and not exposed to gender-affirming hormone therapy (GAHT). Results 7 of the 1333 patients on hormone therapy had an incidence of pancreatitis. 0 of the 615 patients with no history of GAHT use developed pancreatitis. Representing a 6.96 (95% CI 2.76 to 848.78) for the development of pancreatitis in patients with exposure to GAHT therapy. Conclusion Clinicians working with GNC individuals should be aware of this possible association Data are available upon reasonable request.","PeriodicalId":9235,"journal":{"name":"BMJ Open Gastroenterology","volume":"96 1","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMJ Open Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/bmjgast-2023-001312","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background There is limited data on the incidence of gastrointestinal-specific pathology in gender non-conforming (GNC) populations. Methods Retrospective analysis of pancreatitis incidence rates in transgender and GNC persons exposed and not exposed to gender-affirming hormone therapy (GAHT). Results 7 of the 1333 patients on hormone therapy had an incidence of pancreatitis. 0 of the 615 patients with no history of GAHT use developed pancreatitis. Representing a 6.96 (95% CI 2.76 to 848.78) for the development of pancreatitis in patients with exposure to GAHT therapy. Conclusion Clinicians working with GNC individuals should be aware of this possible association Data are available upon reasonable request.
接受激素治疗的不同性别和变性患者胰腺炎发病率增加:一项病例系列研究
背景 有关性别不符(GNC)人群胃肠道特异性病变发病率的数据十分有限。方法 对接受和未接受性别确认激素疗法(GAHT)的变性人和 GNC 患者的胰腺炎发病率进行回顾性分析。结果 在接受激素治疗的 1333 名患者中,有 7 人发生了胰腺炎。在 615 名没有使用过 GAHT 的患者中,0 人患胰腺炎。接受过 GAHT 治疗的患者胰腺炎发病率为 6.96(95% CI 2.76 至 848.78)。结论 临床医生在治疗 GNC 患者时应注意这种可能的关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
BMJ Open Gastroenterology
BMJ Open Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
5.90
自引率
3.20%
发文量
68
审稿时长
2 weeks
期刊介绍: BMJ Open Gastroenterology is an online-only, peer-reviewed, open access gastroenterology journal, dedicated to publishing high-quality medical research from all disciplines and therapeutic areas of gastroenterology. It is the open access companion journal of Gut and is co-owned by the British Society of Gastroenterology. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around continuous publication, publishing research online as soon as the article is ready.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信