A randomized control trial investigating the effectiveness of a commercial pneumonia vaccine (part I): Pre-weaned lambs

IF 1.6 3区农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Small Ruminant Research Pub Date : 2024-04-12 DOI:10.1016/j.smallrumres.2024.107268

M.D. Gardner , J. Van Donkersgoed , C.A. Bauman , M.T. Spinato

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引用次数: 0

Abstract

The objective of this controlled vaccine field trial was to determine the effectiveness of a commercial bacterin in increasing colostral immunity to reduce the risk of bacterial pneumonia in pre-weaned lambs in a commercial sheep operation. Pregnant ewes were randomly allocated to vaccination group (Ovipast™ Plus bacterin, n = 1807; unvaccinated, n = 1812). Ewe vaccination did not significantly (P > 0.05) improve lamb pneumonia treatment rates, crude or pneumonia specific mortality rates, or body weight gain. Interestingly, as birth weight increased in lambs from vaccinated ewes, they gained significantly more than lambs from unvaccinated ewes (P = 0.01). There was no difference in culture results from pneumonic lung samples for either Mannheimia haemolytica (P = 0.89) or Bibersteinia trehalosi (P = 1.00) between lambs from vaccinated and unvaccinated ewes. The results of this study suggest that there was no animal health and welfare benefit from vaccinating ewes with the Ovipast™ Plus bacterin prior to parturition to boost colostral immunity and improve health and growth in their lambs.

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随机对照试验：调查商用肺炎疫苗的有效性（第一部分）：断奶前羔羊

这项疫苗田间对照试验的目的是确定一种商用细菌素在提高初乳免疫力以降低商业化养羊场断奶前羔羊患细菌性肺炎风险方面的效果。怀孕母羊被随机分配到疫苗接种组（Ovipast™ Plus 细菌素，n = 1807；未接种，n = 1812）。母羊接种疫苗后，羔羊肺炎治疗率、粗死亡率或肺炎特异死亡率以及体重增加均无明显改善（P > 0.05）。有趣的是，随着接种疫苗的母羊所产羔羊出生体重的增加，它们的增重明显高于未接种疫苗的母羊所产羔羊（P = 0.01）。接种过疫苗和未接种疫苗的母羊所产羔羊肺部样本中的溶血性曼氏菌（P = 0.89）或三卤贝贝氏菌（P = 1.00）培养结果均无差异。本研究结果表明，在母羊分娩前接种 Ovipast™ Plus 细菌素以提高母羊的初乳免疫力并改善羔羊的健康和生长状况，对动物健康和福利没有益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Small Ruminant Research 农林科学-奶制品与动物科学

CiteScore

3.10

自引率

11.10%

发文量

210

审稿时长

12.5 weeks

期刊介绍： Small Ruminant Research publishes original, basic and applied research articles, technical notes, and review articles on research relating to goats, sheep, deer, the New World camelids llama, alpaca, vicuna and guanaco, and the Old World camels. Topics covered include nutrition, physiology, anatomy, genetics, microbiology, ethology, product technology, socio-economics, management, sustainability and environment, veterinary medicine and husbandry engineering.