Trends Favoring an Anatomical Approach to Radiofrequency Catheter Ablation of Idiopathic Ventricular Arrhythmias Originating From the Left Ventricular Summit

Takumi Yamada, G. Neal Kay
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Abstract

BACKGROUND:Epicardial radiofrequency catheter ablation (RFCA) of idiopathic ventricular arrhythmias (VAs) originating from the left ventricular summit (LVS) is challenging because of the anatomic barriers. On the other hand, RFCA at the endocardial sites near the earliest epicardial activation site of LVS-VAs (anatomic approach) has proven successful. The evolving trends in the approaches and outcomes of RFCA of LVS-VAs at a single center were evaluated.METHODS:We studied 88 consecutive patients with idiopathic LVS-VAs at our institute from 2009 to 2019. These patients were divided into 3 periods: 2009 to 2012 (early), 2013 to 2015 (middle), and 2016 to 2019 (recent). The data were compared among the 3 periods.RESULTS:The RFCA success rate did not significantly change from the early-to-middle period but significantly increased from the middle-to-recent period (P=0.0315). The transpericardial approach usage significantly decreased over the 3 periods. The anatomic approach usage significantly increased over the 3 periods. The use of the transpericardial approach did not affect the RFCA outcomes over the 3 periods. The success rate of the anatomic RFCA tended to increase from the early-to-middle period and significantly increased from the middle-to-recent period (P=0.0412). The number of endocardial locations where RFCA was successful increased over the 3 periods.CONCLUSIONS:Over the 10-year period, the transpericardial approach became decreasingly performed, whereas the anatomic approach became increasingly performed with a satisfactory improvement in the RFCA outcomes of LVS-VAs. The anatomic RFCA became more successful by identifying more and various endocardial locations as target sites.
采用解剖学方法射频导管消融源自左心室峰的特发性室性心律失常的发展趋势
背景:由于解剖障碍,对源于左心室顶部(LVS)的特发性室性心律失常(VAs)进行心外膜射频导管消融(RFCA)具有挑战性。另一方面,在 LVS-VAs 的最早心外膜激活点附近的心内膜部位进行 RFCA(解剖方法)已被证明是成功的。方法:我们研究了 2009 年至 2019 年在我院连续就诊的 88 例特发性 LVS-VA 患者。这些患者被分为 3 个时期:2009 年至 2012 年(早期)、2013 年至 2015 年(中期)和 2016 年至 2019 年(近期)。结果:从早期到中期,RFCA 成功率没有显著变化,但从中期到近期,RFCA 成功率显著上升(P=0.0315)。经心包途径的使用率在三个时期内明显下降。解剖方法的使用率在这三个时期明显增加。经心包途径的使用在 3 个时期内均未影响 RFCA 的结果。解剖型 RFCA 的成功率从早期到中期呈上升趋势,从中期到晚期则显著上升(P=0.0412)。结论:10 年间,经心包入路的手术越来越少,而解剖入路的手术越来越多,LVS-VAs 的 RFCA 结果得到了令人满意的改善。通过确定更多不同的心内膜位置作为靶点,解剖型 RFCA 取得了更大的成功。
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