In silico screening of potential agonists of a glucagon-like peptide-1 receptor among female sex hormone derivatives

Miroslava Nedyalkova, Ralitsa Robeva, Julia Romanova, Kirila Yovcheva, Marco Lattuada, Vasil Simeonov
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Abstract

Glucagon-like peptide-1 (GLP-1) is an intestinal hormone that exerts its pleiotropic effects through a specific GLP-1 receptor (GLP-1R). The hormone–receptor complex might regulate glucose-dependen...
雌性激素衍生物中胰高血糖素样肽-1 受体潜在激动剂的硅学筛选
胰高血糖素样肽-1(GLP-1)是一种肠道激素,通过特定的GLP-1受体(GLP-1R)发挥其多效应。这种激素-受体复合物可能会调节葡萄糖依赖性,从而导致血糖升高。
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