Role of Povidone-Iodine in Reducing Surgical Site Infection

IF 3.1 4区医学 Q2 INFECTIOUS DISEASES

Current Infectious Disease Reports Pub Date : 2024-04-11 DOI:10.1007/s11908-024-00841-z

A. Haleem, C. L. Abad

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引用次数: 0

Abstract

Purpose of Review

Surgical site infections (SSIs) are associated with significant morbidity and mortality. Given the role of endogenous carriage of Staphylococcus aureus, current patient decolonization strategies revolve around the application of topical antiseptic agents prior to and at the time of surgery.

Recent Findings

Intranasal single-application povidone-iodine (PVP-I) on the day of surgery is an emerging, attractive alternative to the established approach of a 5-day course of intranasal mupirocin for preoperative decolonization.

Summary

PVP-I appears more convenient and cost-effective for both patients and healthcare systems, and its role in reducing SSI is under investigation. However, most published literature consists of retrospective, single-center studies primarily done in orthopedic surgical populations. Based on current data, PVP-I appears to be as equally effective in SSI reduction as mupirocin, but larger and better-quality studies are needed to implement a change from currently established preoperative decontamination practices.

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聚维酮碘在减少手术部位感染中的作用

综述目的手术部位感染（SSI）与严重的发病率和死亡率有关。鉴于金黄色葡萄球菌的内源性携带作用，目前的患者去菌策略主要是在手术前和手术时使用局部消毒剂。近期发现在手术当天鼻内单次使用聚维酮碘（PVP-I）是一种新兴的、有吸引力的方法，可替代术前使用莫匹罗星进行 5 天疗程的既定方法。然而，大多数已发表的文献都是主要针对骨科手术人群进行的回顾性单中心研究。根据目前的数据，PVP-I 在减少 SSI 方面似乎与莫匹罗星同样有效，但要改变目前既定的术前消毒做法，还需要进行更大规模和质量更高的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Infectious Disease Reports INFECTIOUS DISEASES-

CiteScore

6.70

自引率

0.00%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of infectious disease. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as HIV/AIDS, sexually transmitted diseases, tropical and travel medicine, and urinary tract infections. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists.