Engineering a Pathway to Glucose-Responsive Therapeutics

IF 6.2 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes Pub Date : 2024-04-12 DOI:10.2337/dbi23-0029

Matthew J. Webber

引用次数: 0

Abstract

In 2014, the American Diabetes Association instituted a novel funding paradigm to support diabetes research through its Pathway to Stop Diabetes® Program. Pathway took a multifaceted approach to provide key funding to diabetes researchers in advancing a broad spectrum of research programs centered on all aspects of understanding, managing, and treating diabetes. Herein the personal perspective of a 2019 Pathway Accelerator awardee is offered, describing a research program seeking to advance a materials-centered approach to engineering glucose-responsive devices and new delivery tools for better therapeutic outcomes in treating diabetes. This is offered alongside a personal reflection on five years of support from the ADA Pathway Program.

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通向葡萄糖反应性疗法的工程学途径

2014 年，美国糖尿病协会（American Diabetes Association）通过其 Pathway to Stop Diabetes® 计划推出了一种新的资助模式来支持糖尿病研究。Pathway 采取多方面的方法，为糖尿病研究人员提供关键资金，以推进以了解、管理和治疗糖尿病的各个方面为中心的广泛研究计划。在此，我们将从 2019 年 Pathway Accelerator 获奖者的个人角度出发，介绍一项研究计划，该计划旨在推进以材料为中心的方法，设计葡萄糖响应设备和新的传输工具，从而在治疗糖尿病方面取得更好的疗效。本文还对 ADA Pathway 计划五年来提供的支持进行了个人反思。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes 医学-内分泌学与代谢

CiteScore

12.50

自引率

2.60%

发文量

1968

审稿时长

1 months

期刊介绍： Diabetes is a scientific journal that publishes original research exploring the physiological and pathophysiological aspects of diabetes mellitus. We encourage submissions of manuscripts pertaining to laboratory, animal, or human research, covering a wide range of topics. Our primary focus is on investigative reports investigating various aspects such as the development and progression of diabetes, along with its associated complications. We also welcome studies delving into normal and pathological pancreatic islet function and intermediary metabolism, as well as exploring the mechanisms of drug and hormone action from a pharmacological perspective. Additionally, we encourage submissions that delve into the biochemical and molecular aspects of both normal and abnormal biological processes. However, it is important to note that we do not publish studies relating to diabetes education or the application of accepted therapeutic and diagnostic approaches to patients with diabetes mellitus. Our aim is to provide a platform for research that contributes to advancing our understanding of the underlying mechanisms and processes of diabetes.

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