Chimeric antigen receptor T cells in the fast lane among autoimmune disease therapies

IF 4.6 2区医学 Q2 IMMUNOLOGY

Clinical & Translational Immunology Pub Date : 2024-04-12 DOI:10.1002/cti2.1502

Zhoujie Ding, David Tarlinton

引用次数: 0

Abstract

In this commentary, we highlight recent studies demonstrating the feasibility and promise of chimeric antigen receptor (CAR) T-cell therapy in treating a number of autoimmune disorders including systemic lupus erythematosus and compare CAR T cells to other therapies aimed at depleting B-lineage cells in treating such diseases.

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嵌合抗原受体 T 细胞驶入自身免疫性疾病疗法的快车道

在这篇评论中，我们重点介绍了最近的一些研究，这些研究证明了嵌合抗原受体（CAR）T细胞疗法在治疗包括系统性红斑狼疮在内的多种自身免疫性疾病方面的可行性和前景，并将CAR T细胞与其他旨在消耗B系细胞以治疗此类疾病的疗法进行了比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical & Translational Immunology Medicine-Immunology and Allergy

CiteScore

12.00

自引率

1.70%

发文量

审稿时长

13 weeks

期刊介绍： Clinical & Translational Immunology is an open access, fully peer-reviewed journal devoted to publishing cutting-edge advances in biomedical research for scientists and physicians. The Journal covers fields including cancer biology, cardiovascular research, gene therapy, immunology, vaccine development and disease pathogenesis and therapy at the earliest phases of investigation.