Stability and shelf-life studies in Ayurvedic medicine: Triphala

Abstract

Triphala is a globally recognized polyherbal Ayurvedic medicine with abundant antioxidants. It is believed to boost the immune system, improve digestion, and address chronic ulcers. The tablets are specially designed for oral consumption and contain herbal ingredients known for their specific medicinal benefits. Storage conditions can significantly affect the shelf life of herbal tablets; therefore, it is essential to assess the stability of these tablets. According to ICH guidelines, Triphala tablets endured accelerated stability studies at 40 °C and a relative humidity (RH) of 75%±5 over a period of 6 months, with assessments conducted at the 2 nd , 4 th , and 6 th months. Various parameters, including organoleptic characteristics, physico-chemical properties, proximate composition, active phytochemical content, and microbiological load, were monitored during these intervals. The results of these analyses were taken into consideration when estimating the shelf life of Triphala Tablets. The extended shelf life estimate was determined by applying an accelerated deterioration rate of 10% for physico-chemical parameters. As a result, it was established that the Triphala tablets have an estimated shelf life of 4 years and 3 months.