An Article on Curcumin Loaded Transferosomes as A Novel Drug Delivery System

Abstract

Curcumin is a natural compound found in turmeric and has shown potential in treating a variety of diseases due to its anti-inflammatory and antioxidant properties. However, curcumin has low bioavailability and poor solubility in water, which limits its therapeutic efficacy. Transferosomes are specialized lipid vesicles that can encapsulate drugs and other bioactive molecules, allowing them to be delivered to specific target tissues. Curcumin, a natural compound found in turmeric, has been the subject of intense study due to its potential health benefits, including anti-inflammatory and antioxidant properties. Transferosomes are lipid-based nanoparticles that can encapsulate hydrophobic compounds like curcumin and improve their delivery to target tissues. They can also enhance the absorption of drugs through the skin or mucous membranes. Several studies have investigated the potential of curcumin loaded transferosomes in various applications, such as wound healing, cancer treatment, and anti-inflammatory therapy. These studies have shown promising results, indicating that transferosomes could be an effective drug delivery system for curcumin. However, more research is needed to optimize the formulation and improve the stability and shelf-life curcumin-loaded transferosomes. Additionally, the safety and toxicity of these nanoparticles need to be thoroughly evaluated before they can be used in clinical application. In our study we have observed drug content 4.47mg/ml and EE% was found to be 94.8%, the percentage of drug release of curcumin transferosomes was observed as 30.8%at time period of 4hr.