STUDY OF CLINICAL PROFILE OF ADULT PATIENTS UNDERGOING PLASMAPHERESIS AT TERTIARY CARE CENTER

Abstract

Introduction: Plasmapheresis is therapeutic procedure that involves extracorporeal removal, return or exchange of blood or plasma products. It is an intensive care procedure that requires appropriate decision, specialized skill based training, close monitoring, and follow-up for best clinical outcomes. Aims And Objective: Identify clinical proles of patient and their relation to clinical output with plasmapheresis, Review the potential complications and clinical signicance of plasmapheresis. Material And Methods: Indoor Patients of various neurological, autoimmune diseases in Tertiary government hospital, which full the criteria for study. Result And Observations: It was observed during study that GBS-AIDP( acute inammatory demyelinating polyneuropathy) was the most common disease in patient undergoing plasmapheresis. Metabolic syndrome (obesity/diabetes/hypertension) were among the highest associated comorbidities. However, no statistically signicant association was seen between age, sex, occupation, comorbidity such as hypertension, obesity and hypothyroidism in present study. (p>0.05). Discussion: It was observed during study that out of 30 patient who underwent plasmapheresis, Positive correlation was found in AIDP incidence and Hba1c level >5.6%. Poor prognosis was found in patients with baseline CRP level >30mg% compared to those with <30mg. However, larger trials with bigger sample size should be carried out to conrm this nding from our study