Antioxidant Activity of Ocimum gratissimum Stem Extract Mediated Silver Nanoparticles- An in Vitro Study

Abstract

Silver nanoparticles made from plant extracts have drawn a lot of interest because of the potential uses for them in nanotechnology and medicine. Ocimum gratissimum was used since the ancient past for its antioxidant, antibacterial, anti-inflammatory, and immunomodulatory properties and it has long been employed in herbal therapy. Ocimum gratissimum’s stem extract was used in several research to synthesize silver nanoparticles and assess their antioxidant properties. The antioxidant capacity of the stem extract is influenced by the phytochemicals found in it, including phenolic substances, flavonoids, and tannins. These phytochemicals have the ability to stabilize the synthesized nanoparticles and serve as reducing agents. The DPPH radical scavenging activity and Hydroxyl radical scavenging activity was used to evaluate the antioxidant activity of the synthesized silver nanoparticles. The results of the conducted assays shows that the Ocimum gratissimum silver nanoparticles has shown to possess significant antioxidant activity and can be used as a therapeutic alternative to the commercial antioxidant drugs.