A Comparative Study Between The Levels of Adropin in Iraqi Women with Metabolic Syndrome and Diabetes

Ibn AL-Haitham Journal For Pure and Applied Sciences Pub Date : 2024-01-20 DOI:10.30526/37.1.3142

Riyam Hussien Assaf, Layla Othman Farhan

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Abstract

By measuring Adropin, fasting blood glucose (FBG), cholesterol, high-density lipoprotein (HDL), triglycerides (TG), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) in the sera of Iraqi patients with MetS and type 2 diabetes mellitus (T2DM), the current study was designed to compare some crucial markers in metabolic syndrome (MetS) sera and diabetic patients (T2DM) with control. Twenty female subjects were divided into three groups: group I=40 with MetS and group II=40 with T2DM, and 40 healthy subjects were employed as a control group. Compared to the control group, Adropin levels in the Mets group and T2DM group decreased significantly (p < 0.05). In contrast, none of the patient groups (MetS and T2DM) showed any change compared to themselves. In conclusion, according to the present data, higher levels of FBG, lipid profile, and increased blood pressure (BP) were found in patients with MetS and T2DM. A drop in level could be considered a novel indicator of MetS and T2DM. Compared to T2DM patients, Adropin levels are thought to have a more sensitive diagnostic function than those with MetS and newly diagnosed DM.

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患有代谢综合征和糖尿病的伊拉克妇女体内阿托品水平的比较研究

本研究旨在通过测量伊拉克 MetS 和 2 型糖尿病（T2DM）患者血清中的阿托品、空腹血糖（FBG）、胆固醇、高密度脂蛋白（HDL）、甘油三酯（TG）、低密度脂蛋白（LDL）和极低密度脂蛋白（VLDL），将代谢综合征（MetS）和糖尿病患者（T2DM）血清中的一些重要指标与对照组进行比较。20 名女性受试者被分为三组：第一组=40 名代谢综合征患者，第二组=40 名 T2DM 患者，40 名健康受试者作为对照组。与对照组相比，美特斯邦威组和 T2DM 组的 Adropin 水平明显下降（P < 0.05）。相比之下，所有患者组（MetS 组和 T2DM 组）均未出现任何变化。总之，根据目前的数据，MetS 和 T2DM 患者的 FBG 和血脂水平较高，血压（BP）升高。血脂水平的下降可被视为 MetS 和 T2DM 的新指标。与 T2DM 患者相比，Adropin 水平被认为具有更灵敏的诊断功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ibn AL-Haitham Journal For Pure and Applied Sciences

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