Pattern of Pre-Anesthetic Medications Used In Various Surgical Specialties in A Tertiary Care Hospital

Rosi Pradhan, Anil Maharjan, Bibena Lamichhane, A. Bhochhibhoya, U. Laudari, Anjan Khadka, Ashmita Bhochhibhoya, Parichhya Bista, Aditya Kumar Jha
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Abstract

Introduction: Most of the surgeries done in our country under anesthesia are mostly at urban region and very low number at remote areas. Even those surgeries done under anesthesia do not receive proper premedication. Pre-anesthetic medicine has been linked to a variety of outcomes, including postoperative recovery time, the need for postoperative analgesia, and hospital stay. Yet, we have very less data regarding the patterns of use of drugs for premedication. Methods: It is a cross-sectional descriptive study performed in the department of Anesthesiology at KIST Medical College and Teaching Hospital from 15th Feb 2022 till 14th Feb 2023, after obtaining ethical clearance from the Institutional Review Committee. The total sample size was 385 which were calculated using Cochrane formula. All the patients who belonged to American Society of Anesthesiologists (ASA) I-III undergoing elective surgical procedures and administered premedication were selected for the study only after their informed written consent. Results: Out of 496 cases, 385 (53.8%) of patients were selected and pre-medications were recorded. The premedication used were metoclopramide 375 (97.4%), pantoprazole 375 (97.4%), paracetamol 52 (13.5%), glycopyrrolate 26 (6.75%), pregabalin 21 (5.45%), alprazolam 20 (5.19%), and lorazepam 1 (0.25%).  Types of surgeries categorizations were 59.22 % general surgery, 17.92 % Gynecological and Obstetrics, 17.14 % Orthopedic cases, 4.67 % ENT and 1.04 % dental cases. Conclusion: The most commonly administered pre-anesthetic drugs were metoclopramide, pantoprazole, paracetamol, pregabalin, alprazolam and then lorazepam.
一家三甲医院各外科使用麻醉前药物的模式
简介在我国,大部分麻醉手术都是在城市地区进行的,偏远地区的手术数量很少。即使是在麻醉下进行的手术,也没有进行适当的术前用药。麻醉前用药与多种结果有关,包括术后恢复时间、术后镇痛需求和住院时间。然而,我们对麻醉前用药的使用模式却知之甚少:这是一项横断面描述性研究,于 2022 年 2 月 15 日至 2023 年 2 月 14 日在韩国科学技术院医学院和教学医院麻醉科进行,此前已获得机构审查委员会的伦理许可。总样本量为 385 份,采用 Cochrane 公式计算。所有属于美国麻醉医师协会(ASA)I-III级、接受择期手术并使用预处理药物的患者均在知情书面同意后才被选入研究:在 496 个病例中,有 385 例(53.8%)患者被选中并记录了术前用药情况。使用的术前药物有甲氧氯普胺 375(97.4%)、泮托拉唑 375(97.4%)、扑热息痛 52(13.5%)、甘草酸苷 26(6.75%)、普瑞巴林 21(5.45%)、阿普唑仑 20(5.19%)和劳拉西泮 1(0.25%)。 手术类型分类为:普外科 59.22%、妇产科 17.92%、骨科 17.14%、耳鼻喉科 4.67%、牙科 1.04%:最常使用的麻醉前药物是甲氧氯普胺、泮托拉唑、扑热息痛、普瑞巴林、阿普唑仑,然后是劳拉西泮。
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