The Influence of the Clinical Pharmacist in the Management of Depression: A Systematic Review

Bárbara Mendes Paz Chao, Amanda Razera, Maria Fernanda Lopes, Suellen Aparecida Grosko, Amanda Makohin Machado, M. Cordeiro, Luciana Erzinger Alves de Camargo, Catiuscie Cabreira da Silva Tortorella, A. Bini
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Abstract

Background: Mental disorders are among the top ten causes of overload in health systems worldwide. Although traditional pharmaceutical interventions have proven effective in treating depression, the role of the pharmacist in personalized pharmaceutical care for depressed patients is still an emerging area of research and clinical practice, which may be even more effective. Methods: This study aimed to perform an integrative literature review using the NCBI/PubMed and EMBASE databases, in articles published until the year 2023, according to pre-established inclusion and exclusion criteria. Results: 360 publications were identified. Following the eligibility criteria, 210 duplicate publications were excluded and 145 were discarded because they did not meet the pre-established eligibility criteria. Thus, 5 original articles from 3 countries were included in the present study. Conclusion: According to the publications analyzed, it is demonstrated that depression has better response when there is pharmaceutical intervention, as well as multiprofessional. It is noted that factors such as adherence to treatment, control of adverse events related to medications, and quality of life of the patient are directly influenced by the intervention of the clinical pharmacist.
临床药剂师在抑郁症管理中的影响:系统回顾
背景:精神障碍是造成全球医疗系统负担过重的十大原因之一。尽管传统的药物干预已被证明对治疗抑郁症有效,但药剂师在抑郁症患者个性化药物护理中的作用仍是一个新兴的研究和临床实践领域,它可能更加有效。方法:本研究旨在利用 NCBI/PubMed 和 EMBASE 数据库,按照预先确定的纳入和排除标准,对 2023 年之前发表的文章进行综合文献综述。研究结果确定了 360 篇出版物。根据资格标准,排除了 210 篇重复出版物,145 篇因不符合预先设定的资格标准而被剔除。因此,本研究纳入了来自 3 个国家的 5 篇原创文章。研究结论根据所分析的出版物,抑郁症患者在接受药物干预和多专业治疗时会有更好的反应。我们注意到,临床药剂师的干预会直接影响患者的治疗依从性、与药物相关的不良反应控制和生活质量等因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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