E. O. Medusheva, Y. Fidorovskaya, M. A. Shchedrina, N. D. Oltarzhevskaya
{"title":"A modern polymer based wound care coating for wound management","authors":"E. O. Medusheva, Y. Fidorovskaya, M. A. Shchedrina, N. D. Oltarzhevskaya","doi":"10.25199/2408-9613-2023-10-2-24-31","DOIUrl":null,"url":null,"abstract":"Pain management at phase 1 of the wound process includes wound cleaning due to the lysis of purulent-necrotic masses, control of the pathogenic microflora, and evacuation of wound discharge. These factors are achievable with a new composite depo-material having the textile base, hydrogel composition based on biopolysaccharide sodium alginate with immobilized active components – proteolytic enzyme of plant origin- papain and antimicrobial salt-like silver. Biosynthesis of silver nanoparticles and its presence in the composition in the cation form increases efficacy and eliminates toxicity of the treatment due to low silver concentration.","PeriodicalId":366300,"journal":{"name":"Wounds and wound infections. The prof. B.M. Kostyuchenok journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wounds and wound infections. The prof. B.M. Kostyuchenok journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25199/2408-9613-2023-10-2-24-31","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Pain management at phase 1 of the wound process includes wound cleaning due to the lysis of purulent-necrotic masses, control of the pathogenic microflora, and evacuation of wound discharge. These factors are achievable with a new composite depo-material having the textile base, hydrogel composition based on biopolysaccharide sodium alginate with immobilized active components – proteolytic enzyme of plant origin- papain and antimicrobial salt-like silver. Biosynthesis of silver nanoparticles and its presence in the composition in the cation form increases efficacy and eliminates toxicity of the treatment due to low silver concentration.