The influence of carbofuran insecticide exposure on the number of type II Lung Cells in Mice (Mus musculus)

Abstract

The aim of this research was to demonstrate lung histopathological damage in mice (Mus musculus) caused by carbofuran exposure. Twenty female mice (Mus musculus) aged 10 weeks with a body weight of 25-30 g were used in the study. The mice were divided into four groups: P0, P1, P2, and P3. All samples received 0.5 ml/day of physiological NaCl, and P1, P2, and P3 were additionally exposed to carbofuran at doses of 0.0208, 0.0417, and 0.0833 mg/kg body weight of mice/day, respectively. This treatment was carried out for 10 days. Data analysis was performed using ANOVA followed by the BNJ test. The results showed an increase in necrotic type II cells with increasing doses of carbofuran.