Health-related quality of life among congestive heart failure patients with preserved and reduced ejection fraction

Dian Hudiyawati, Kartinah, Afidatul Mujannidah
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Abstract

To determine factors that affect the health-related quality of life (HRQOL) of congestive heart failure (CHF) patients with preserved and reduced ejection fraction. A cross-sectional study design was used for this study. The stratified random sampling was applied for each subgroup. HRQOL was measured with the Minnesota Living with Heart Failure Questionnaire. The data were analyzed using chi-square, Spearman’s correlation analysis, and independent t-test. A number of 67 respondents participated in the recent study. The total mean scores of HRQOL were significantly different (P = 0.001) between heart failure (HF) patients with reduced and preserved ejection fractions, 41.07 ± 7.54 and 54.97 ± 4.36, respectively. It related with the physical (mean ± standard deviation [SD] = 10.4 ± 2.14; t = −10.08, 95% CI = −12.46 to −8.34; P-value = 0.001) and psychological (mean ± SD = 3.5 ± 0.5; t = −6.68, 95% CI = −4.55 to −2.45; P-value = 0.001) domain. Strong correlation was found between age (r = −0.898, P < 0.05), NYHA functional classes (r = −0.858, P < 0.01), duration of HF (r = −0.807, P < 0.01), family support (r = 0.927, P < 0.01), and quality of life (QoL). HRQOL in HF patients with reduced ejection fraction was higher than in those with preserved ejection fraction. Family support is a further determinant factor that has a positive correlation to the QoL.
射血分数保留和降低的充血性心力衰竭患者的健康相关生活质量
目的:确定影响射血分数保留和降低的充血性心力衰竭(CHF)患者健康相关生活质量(HRQOL)的因素。 本研究采用横断面研究设计。每个亚组采用分层随机抽样。HRQOL 采用明尼苏达心衰患者生活问卷进行测量。数据采用卡方检验、斯皮尔曼相关分析和独立 t 检验进行分析。 共有 67 名受访者参与了近期的研究。射血分数降低和保留的心力衰竭(HF)患者的 HRQOL 平均总分(41.07 ± 7.54 和 54.97 ± 4.36)有显著差异(P = 0.001)。它与身体(平均±标准差 [SD] = 10.4 ± 2.14;t = -10.08,95% CI = -12.46 至 -8.34;P 值 = 0.001)和心理(平均±标准差 = 3.5 ± 0.5;t = -6.68,95% CI = -4.55 至 -2.45;P 值 = 0.001)领域相关。年龄(r = -0.898,P <0.05)、NYHA 功能分级(r = -0.858,P <0.01)、HF 病程(r = -0.807,P <0.01)、家庭支持(r = 0.927,P <0.01)与生活质量(QoL)之间存在很强的相关性。 射血分数降低的心房颤动患者的 HRQOL 高于射血分数保留的患者。家庭支持是另一个与生活质量呈正相关的决定性因素。
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