ULASAN SISTEMATIK KEATAS PENGAPLIKASIAN BIOPENDERIA BERASASKAN PERENCATAN ENZIM SEBAGAI KAEDAH SARINGAN AWAL UNTUK PEMANTAUAN ALAM SEKITAR DAN KESELAMATAN MAKANANEMANTAUAN ALAM SEKITAR DAN KESELAMATAN MAKANAN
M. K. Sabullah, R. Abdullah, Roslina Jawan, Lucky Goh Poh Wah, Hartinie Marbawi, Syed Umar Faruq Syed Najmuddin, Jualang Azlan Gansau, Mohd Yunus Syukor
{"title":"ULASAN SISTEMATIK KEATAS PENGAPLIKASIAN BIOPENDERIA BERASASKAN PERENCATAN ENZIM SEBAGAI KAEDAH SARINGAN AWAL UNTUK PEMANTAUAN ALAM SEKITAR DAN KESELAMATAN MAKANANEMANTAUAN ALAM SEKITAR DAN KESELAMATAN MAKANAN","authors":"M. K. Sabullah, R. Abdullah, Roslina Jawan, Lucky Goh Poh Wah, Hartinie Marbawi, Syed Umar Faruq Syed Najmuddin, Jualang Azlan Gansau, Mohd Yunus Syukor","doi":"10.11113/jurnalteknologi.v86.20579","DOIUrl":null,"url":null,"abstract":"\n\n\n\nIn this article, the latest discoveries in the development of biosensors based on enzyme inhibition are reviewed. Due to their excellent selectivity and sensitivity, they represent a significant alternative method to conventional analytical methods; which is a method of analysis that only relies on the generation of instrumentation data without any preliminary screening. Basically, biosensors are able to convert biological activity into a quantifiable signal. These enzyme inhibition-based biosensors have a wide range of applications in the fields of environmental safety, food safety, and clinical analysis since toxic substances containing heavy metals and pesticides are the most effective inhibitors of enzymes. This paper is aimed at exploring the methods used and the sensitivity to various inhibitors for biosensors based on the inhibition of enzymes such as glucose oxidase, urease, tyrosinase, cholinesterase, and other enzymes.\n\n\n\n","PeriodicalId":55763,"journal":{"name":"Jurnal Teknologi","volume":"16 9","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jurnal Teknologi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11113/jurnalteknologi.v86.20579","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
In this article, the latest discoveries in the development of biosensors based on enzyme inhibition are reviewed. Due to their excellent selectivity and sensitivity, they represent a significant alternative method to conventional analytical methods; which is a method of analysis that only relies on the generation of instrumentation data without any preliminary screening. Basically, biosensors are able to convert biological activity into a quantifiable signal. These enzyme inhibition-based biosensors have a wide range of applications in the fields of environmental safety, food safety, and clinical analysis since toxic substances containing heavy metals and pesticides are the most effective inhibitors of enzymes. This paper is aimed at exploring the methods used and the sensitivity to various inhibitors for biosensors based on the inhibition of enzymes such as glucose oxidase, urease, tyrosinase, cholinesterase, and other enzymes.