Factors Related to Premature Canities; A Cross-sectional Study in Lagos State, Nigeria

Ezon-Ebidor Innocent Edibamode, Edet Iboro Efiong, Nicholas Asiwe, Cynthia Eben Gobour
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Abstract

Background: Canities, or graying or whitening hair, is a natural part of aging caused by reduced melanin production. Premature canities occur in humans or animals at a young age, with factors such as genetics, lifestyle, and environmental influences contributing. The study aims to evaluate the relationship between ABO Blood type, rhesus Factor, Genotype, Lifestyle, and Premature canities. Methods: 259 respondents were involved and a cross-sectional descriptive study design was used to generate data. The respondents were selected using a multi-stage random sampling techniques and data collection was via descriptive questionnaire. Data obtained were analyzed using IBM SPSS version 25. Results: A study of 259 participants found no significant association between premature canities and ABO blood type, rhesus, and genotype while lifestyle factors like smoking, and alcohol intake showed an association. Canities were found in various head regions, with no differences between sexes. Smoking and alcohol intake were more common in males. Depression was negatively associated with non-premature and premature canities. Nutrition intake was similar, but high carbohydrate and vegetable consumption was found to be statistically different. Conclusion: No association between ABO blood type, rhesus factor, genotype with premature canities, and lifestyle (alcohol intake and smoking) showed possible association with premature canities. 
尼日利亚拉各斯州早产相关因素横断面研究
背景介绍毛发变白或变白是衰老的自然现象,是由于黑色素生成减少造成的。人类或动物在年轻时就会出现早衰,这与遗传、生活方式和环境影响等因素有关。本研究旨在评估 ABO 血型、恒河猴因子、基因型、生活方式与早衰之间的关系。方法:研究涉及 259 名受访者,采用横断面描述性研究设计来生成数据。受访者通过多阶段随机抽样技术选出,并通过描述性问卷收集数据。获得的数据使用 IBM SPSS 25 版进行分析。结果对 259 名参与者进行的研究发现,早发性霰粒肿与 ABO 血型、恒河猴血型和基因型无明显关联,而吸烟和酒精摄入量等生活方式因素则有关联。早衰发生在不同的头部区域,男女之间没有差异。吸烟和饮酒在男性中更为常见。抑郁与非早产儿和早产儿颅骨发育不良呈负相关。营养摄入情况相似,但高碳水化合物和蔬菜的摄入量在统计学上存在差异。结论ABO血型、恒河猴因子、基因型与早产没有关联,而生活方式(酒精摄入量和吸烟)可能与早产有关。
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