Ethanol Sclerotherapy in the Management of Ovarian Endometrioma: Technical Considerations for Catheter- and Needle-Directed Sclerotherapy.

IF 2.8 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Aynur Azizova, Turkmen Turan Ciftci, Murat Gultekin, Emre Unal, Okan Akhan, Gurkan Bozdag, Devrim Akinci
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引用次数: 0

Abstract

Purpose: To provide technical guidance on applying catheter-directed and needle-directed ethanol sclerotherapy for endometriomas and present the results of these sclerotherapy methods.

Materials and methods: From January 2015 to March 2021, the results of the patients with symptomatic ovarian endometriomas who underwent needle-directed or catheter-directed sclerotherapy were evaluated, retrospectively. The decision to apply which sclerotherapy technique was made during the procedure for each patient considering the following factors: cyst size, cyst location, cyst viscosity, and tissue rigidity.

Results: Both needle-directed (n = 34 cysts) and catheter-directed (n = 34 cysts) sclerotherapy techniques were effective, with a 100% technical success rate and a 97% clinical success rate. In two of 34 cysts (6%) treated with needle-directed sclerotherapy, recurrence was detected and successfully retreated with catheter-directed sclerotherapy. Significant reductions in cyst size, pain, and serum cancer antigen 125 levels (p < 0.05) were noted. Serum anti-Müllerian hormone levels remained unaffected, indicating preserved ovarian reserve (p > 0.05). Among those treated for infertility, the pregnancy rate was 54% (n = 6/11). The mean ± SD cyst size decline was greater in catheter-directed sclerotherapy than needle-directed sclerotherapy (5.5 ± 3.1 cm vs. 4.0 ± 2.1 cm, p < 0.05). However, the pretreatment cyst volumes were considerably higher in catheter-directed sclerotherapy group (202.0 ± 233.5 mL vs. 78.8 ± 59.7 mL, p < 0.05) and were associated with significant post-treatment volume decrease (p < 0.05).

Conclusion: The choice between catheter-directed and needle-directed ethanol sclerotherapy should be determined during the procedure, with a preference for catheter-directed sclerotherapy when feasible. Crucial factors in making this decision include cyst size, cyst location, cyst viscosity, and tissue rigidity. Level of evidence Level 3, non-controlled retrospective cohort study.

乙醇硬化疗法治疗卵巢子宫内膜异位症:导管和针导硬化疗法的技术考虑因素。
目的:为子宫内膜异位症应用导管引导和针引导乙醇硬化剂治疗提供技术指导,并展示这些硬化剂治疗方法的效果:从2015年1月至2021年3月,对接受针导或导管导硬化剂治疗的无症状卵巢子宫内膜异位症患者的结果进行了回顾性评估。每位患者在手术过程中都要考虑以下因素:囊肿大小、囊肿位置、囊肿粘度和组织硬度:结果:针刺导向(34 个囊肿)和导管导向(34 个囊肿)两种硬化剂治疗技术均有效,技术成功率为 100%,临床成功率为 97%。在采用针导硬化剂疗法治疗的 34 个囊肿中,有两个囊肿(6%)发现复发,采用导管导引硬化剂疗法成功治疗了这两个囊肿。囊肿大小、疼痛和血清癌抗原 125 水平均显著降低(P 0.05)。在因不孕而接受治疗的患者中,怀孕率为 54%(n = 6/11)。导管导向硬化疗法的平均(±SD)囊肿大小下降幅度大于针头导向硬化疗法(5.5 ± 3.1 厘米 vs. 4.0 ± 2.1 厘米,P 结论:导管导向硬化疗法和针头导向硬化疗法之间的选择是非常重要的:应在手术过程中决定选择导管引导还是针引导乙醇硬化剂注射疗法,在可行的情况下应优先选择导管引导硬化剂注射疗法。做出这一决定的关键因素包括囊肿大小、囊肿位置、囊肿粘度和组织硬度。证据级别 3 级,非对照回顾性队列研究。
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来源期刊
CiteScore
5.50
自引率
13.80%
发文量
306
审稿时长
3-8 weeks
期刊介绍: CardioVascular and Interventional Radiology (CVIR) is the official journal of the Cardiovascular and Interventional Radiological Society of Europe, and is also the official organ of a number of additional distinguished national and international interventional radiological societies. CVIR publishes double blinded peer-reviewed original research work including clinical and laboratory investigations, technical notes, case reports, works in progress, and letters to the editor, as well as review articles, pictorial essays, editorials, and special invited submissions in the field of vascular and interventional radiology. Beside the communication of the latest research results in this field, it is also the aim of CVIR to support continuous medical education. Articles that are accepted for publication are done so with the understanding that they, or their substantive contents, have not been and will not be submitted to any other publication.
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