{"title":"Single peak solutions for an elliptic system of FitzHugh–Nagumo type","authors":"Bingqi Wang, Xiangyu Zhou","doi":"10.1007/s11784-024-01103-0","DOIUrl":null,"url":null,"abstract":"<p>We study the Dirichlet problem for an elliptic system derived from FitzHugh–Nagummo model as follows: </p><span>$$\\begin{aligned} \\left\\{ \\begin{aligned}&-\\varepsilon ^2\\Delta u =f(u)- v, \\qquad&\\text {in}\\ \\Omega ,\\\\&-\\Delta v+\\gamma v =\\delta _\\varepsilon u,&\\text{ in }\\ \\Omega ,\\\\&u=v =0,&\\text {on}\\ \\partial \\Omega , \\end{aligned} \\right. \\end{aligned}$$</span><p>where <span>\\(\\Omega \\)</span> represents a bounded smooth domain in <span>\\(\\mathbb {R}^2\\)</span> and <span>\\(\\varepsilon , \\gamma \\)</span> are positive constants. The parameter <span>\\(\\delta _{\\varepsilon }>0\\)</span> is a constant dependent on <span>\\(\\varepsilon \\)</span>, and the nonlinear term <i>f</i>(<i>u</i>) is defined as <span>\\(u(u-a)(1-u)\\)</span>. Here, <i>a</i> is a function in <span>\\(C^2(\\Omega )\\cap C^1({\\overline{\\Omega }})\\)</span> with its range confined to <span>\\((0,\\frac{1}{2})\\)</span>. Our research focuses on this spatially inhomogeneous scenario whereas the scenario that <i>a</i> is spatially constant has been studied extensively by many other mathematicians. Specifically, in dimension two, we utilize the Lyapunov–Schmidt reduction method to establish the existence of a single interior peak solution. This is contingent upon a mild condition on <i>a</i>, which acts as an indicator of a location-dependent activation threshold for excitable neurons in the biological environment.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1007/s11784-024-01103-0","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
We study the Dirichlet problem for an elliptic system derived from FitzHugh–Nagummo model as follows:
$$\begin{aligned} \left\{ \begin{aligned}&-\varepsilon ^2\Delta u =f(u)- v, \qquad&\text {in}\ \Omega ,\\&-\Delta v+\gamma v =\delta _\varepsilon u,&\text{ in }\ \Omega ,\\&u=v =0,&\text {on}\ \partial \Omega , \end{aligned} \right. \end{aligned}$$
where \(\Omega \) represents a bounded smooth domain in \(\mathbb {R}^2\) and \(\varepsilon , \gamma \) are positive constants. The parameter \(\delta _{\varepsilon }>0\) is a constant dependent on \(\varepsilon \), and the nonlinear term f(u) is defined as \(u(u-a)(1-u)\). Here, a is a function in \(C^2(\Omega )\cap C^1({\overline{\Omega }})\) with its range confined to \((0,\frac{1}{2})\). Our research focuses on this spatially inhomogeneous scenario whereas the scenario that a is spatially constant has been studied extensively by many other mathematicians. Specifically, in dimension two, we utilize the Lyapunov–Schmidt reduction method to establish the existence of a single interior peak solution. This is contingent upon a mild condition on a, which acts as an indicator of a location-dependent activation threshold for excitable neurons in the biological environment.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.