{"title":"Gut motility and its control","authors":"Shona A. McQuilken","doi":"10.1016/j.mpaic.2024.01.005","DOIUrl":null,"url":null,"abstract":"<div><p>To aid the digestion and absorption of nutrients, the gastrointestinal (GI) tract uses a carefully coordinated series of muscular contractions. These contractions serve to propel luminal contents through the tract, as well as churning and mixing them with enzymatic secretions to aid digestion. Smooth muscle of the GI tract exhibits fluctuations in its membrane potential that can lead to action potentials and muscle contraction. These fluctuations, known as the basal electrical rhythm, can range from around three to five per minute in the stomach to 20 per minute in the small intestine. They can be influenced by neural and hormonal input and form the basis of most muscular contractions in the GI tract. The pattern of contractions varies in different parts of the tract to serve the distinct functions of each region, for example, the stomach exhibits a reflex relaxation of muscle to accommodate a meal, while in the small intestine, segmental, mixing contractions predominate.</p></div>","PeriodicalId":45856,"journal":{"name":"Anaesthesia and Intensive Care Medicine","volume":"25 4","pages":"Pages 297-300"},"PeriodicalIF":0.2000,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia and Intensive Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472029924000055","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
To aid the digestion and absorption of nutrients, the gastrointestinal (GI) tract uses a carefully coordinated series of muscular contractions. These contractions serve to propel luminal contents through the tract, as well as churning and mixing them with enzymatic secretions to aid digestion. Smooth muscle of the GI tract exhibits fluctuations in its membrane potential that can lead to action potentials and muscle contraction. These fluctuations, known as the basal electrical rhythm, can range from around three to five per minute in the stomach to 20 per minute in the small intestine. They can be influenced by neural and hormonal input and form the basis of most muscular contractions in the GI tract. The pattern of contractions varies in different parts of the tract to serve the distinct functions of each region, for example, the stomach exhibits a reflex relaxation of muscle to accommodate a meal, while in the small intestine, segmental, mixing contractions predominate.
期刊介绍:
Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.