Gut motility and its control

IF 0.2 Q4 ANESTHESIOLOGY
Shona A. McQuilken
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引用次数: 0

Abstract

To aid the digestion and absorption of nutrients, the gastrointestinal (GI) tract uses a carefully coordinated series of muscular contractions. These contractions serve to propel luminal contents through the tract, as well as churning and mixing them with enzymatic secretions to aid digestion. Smooth muscle of the GI tract exhibits fluctuations in its membrane potential that can lead to action potentials and muscle contraction. These fluctuations, known as the basal electrical rhythm, can range from around three to five per minute in the stomach to 20 per minute in the small intestine. They can be influenced by neural and hormonal input and form the basis of most muscular contractions in the GI tract. The pattern of contractions varies in different parts of the tract to serve the distinct functions of each region, for example, the stomach exhibits a reflex relaxation of muscle to accommodate a meal, while in the small intestine, segmental, mixing contractions predominate.

肠道运动及其控制
为了帮助营养物质的消化和吸收,胃肠道(GI)通过一系列精心协调的肌肉收缩来实现。这些收缩的作用是推动管腔内容物通过胃肠道,并将其与酶分泌物搅动和混合,以帮助消化。消化道平滑肌的膜电位会出现波动,从而导致动作电位和肌肉收缩。这些波动被称为基础电节律,在胃中大约为每分钟 3 到 5 次,在小肠中则为每分钟 20 次。它们会受到神经和荷尔蒙输入的影响,并构成大多数消化道肌肉收缩的基础。胃肠道不同部位的收缩模式各不相同,以满足每个区域的不同功能,例如,胃部肌肉会反射性地放松以适应进餐,而小肠则以节段性混合收缩为主。
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
152
期刊介绍: Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.
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