RANDOMIZED CLINICAL TRIAL OF ASPIRIN AS PROPHYLAXIS FOR THROMBOEMBOLISM IN HIP ARTHROPLASTY.

IF 0.5 4区医学 Q4 ORTHOPEDICS

Acta Ortopedica Brasileira Pub Date : 2024-03-22 eCollection Date: 2024-01-01 DOI:10.1590/1413-785220243201e272229

Raul Carneiro Lins, Epitacio Rolim, Yago Andrade Lima, Rodrigo Rodrigues de Sousa Moura

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引用次数: 0

Abstract

Objective: This study aims to evaluate aspirin as a chemical prophylaxis (200 mg) in total hip arthroplasty.

Methods: the study compared two groups and used ultrasonography (USG) to screen for low-deep venous thrombosis. Group 1 received 600 mg (control), and Group 2 received 200 mg of (intervention), associated with the use of elastic compression stockings and early walking.

Results: fourteen patients were allocated to Group A (200mg), and 16 to Group B (600mg); in group A (200mg), 3 cases with thrombus below the popliteal vein were detected at the first USG examination. All of them are in the left lower limb (21.4%). In group B (600 mg), 5 cases were identified after the first exam (31.2%). All cases were asymptomatic and followed the protocol with prophylaxis only with Aspirin.

Conclusion: In the statistical data, there were no differences in the presence of thrombus between the 200- and 600 mg groups, which is credited to using low-dose aspirin in low doses (200mg). Hematimetric levels returned to baseline levels and suggested there was no chronic or acute bleeding related to the use of aspirin. The manuscript was prepared according to the CONSORT guideline 2010. Level of Evidence I; Longitudinal Randomized Comparative Clinical Study.

查看原文本刊更多论文

阿司匹林作为髋关节置换术血栓栓塞预防药物的随机临床试验。

研究目的本研究旨在评估阿司匹林作为全髋关节置换术的化学预防药物（200 毫克）的效果。方法：本研究对两组患者进行了比较，并使用超声波检查（USG）筛查低位深静脉血栓。结果：14 名患者被分配到 A 组（200 毫克），16 名患者被分配到 B 组（600 毫克）；在 A 组（200 毫克）中，首次 USG 检查发现 3 例腘静脉以下血栓。所有病例均位于左下肢（21.4%）。在 B 组（600 毫克）中，第一次检查后发现了 5 个病例（31.2%）。所有病例均无症状，并按照方案仅使用阿司匹林进行预防：从统计数据来看，200 毫克组和 600 毫克组在出现血栓方面没有差异，这归功于使用了小剂量阿司匹林（200 毫克）。血液化验水平恢复到基线水平，表明没有出现与使用阿司匹林有关的慢性或急性出血。稿件根据 2010 年 CONSORT 指南编写。证据等级 I；纵向随机比较临床研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Ortopedica Brasileira Orthopedics-

CiteScore

0.90

自引率

14.30%

发文量

审稿时长

25 weeks

期刊介绍： A Revista Acta Ortopédica Brasileira, órgão oficial do Departamento de Ortopedia e Traumatologia da Faculdade de Medicina da Universidade de São Paulo (DOT/FMUSP), é publicada bimestralmente em seis edições ao ano (jan/fev, mar/abr, maio/jun, jul/ago, set/out e nov/dez) com versão em inglês disponível nos principais indexadores nacionais e internacionais e instituições de ensino do Brasil. Sendo hoje reconhecidamente uma importante contribuição para os especialistas da área com sua seriedade e árduo trabalho para as indexações já conquistadas.