Developing a Program Costs Checklist of Digital Health Interventions: A Scoping Review and Empirical Case Study.

IF 4.4 3区医学 Q1 ECONOMICS

PharmacoEconomics Pub Date : 2024-06-01 Epub Date: 2024-03-26 DOI:10.1007/s40273-024-01366-y

Zareen Abbas Khan, Kristian Kidholm, Sindre Andre Pedersen, Silje Marie Haga, Filip Drozd, Thea Sundrehagen, Ellen Olavesen, Vidar Halsteinli

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引用次数: 0

Abstract

Introduction: The rate of development and complexity of digital health interventions (DHIs) in recent years has to some extent outpaced the methodological development in economic evaluation and costing. Particularly, the choice of cost components included in intervention or program costs of DHIs have received scant attention. The aim of this study was to build a literature-informed checklist of program cost components of DHIs. The checklist was next tested by applying it to an empirical case, Mamma Mia, a DHI developed to prevent perinatal depression.

Method: A scoping review with a structured literature search identified peer-reviewed literature from 2010 to 2022 that offers guidance on program costs of DHIs. Relevant guidance was summarized and extracted elements were organized into categories of main cost components and their associated activities following the standard three-step approach, that is, activities, resource use and unit costs.

Results: Of the 3448 records reviewed, 12 studies met the criteria for data extraction. The main cost categories identified were development, research, maintenance, implementation and health personnel involvement (HPI). Costs are largely considered to be context-specific, may decrease as the DHI matures and vary with number of users. The five categories and their associated activities constitute the checklist. This was applied to estimate program costs per user for Mamma Mia Self-Guided and Blended, the latter including additional guidance from public health nurses during standard maternal check-ups. Excluding research, the program cost per mother was more than double for Blended compared with Self-Guided (€140.5 versus €56.6, 2022 Euros) due to increased implementation and HPI costs. Including research increased the program costs to €190.8 and €106.9, respectively. One-way sensitivity analyses showed sensitivity to changes in number of users, lifespan of the app, salaries and license fee.

Conclusion: The checklist can help increase transparency of cost calculation and improve future comparison across studies.

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制定数字健康干预项目成本清单：范围审查与经验案例研究》。

简介近年来，数字健康干预措施（DHIs）的发展速度和复杂程度在一定程度上超过了经济评估和成本计算方法的发展速度。特别是，数字医疗干预措施或项目成本中的成本构成选择很少受到关注。本研究的目的是根据文献资料，为直接保健措施的项目成本组成部分建立一个核对表。下一步，我们将把该核对表应用于一个经验案例，即为预防围产期抑郁症而开发的 "妈妈咪呀"（DHI），以对该核对表进行测试：方法：通过结构化文献检索进行范围审查，确定了 2010 年至 2022 年间同行评议的文献，这些文献为 DHI 的项目成本提供了指导。对相关指南进行了总结，并按照标准的三步法（即活动、资源使用和单位成本），将提取的要素整理成主要成本构成及其相关活动的类别：在审查的 3448 条记录中，有 12 项研究符合数据提取标准。确定的主要成本类别包括开发、研究、维护、实施和医务人员参与（HPI）。成本在很大程度上被认为是因地制宜的，可能会随着 DHI 的成熟而降低，并随着用户数量的变化而变化。这五个类别及其相关活动构成了核对表。在估算 "妈妈咪呀自我指导 "和 "混合指导 "的每位用户的项目成本时采用了这一方法，后者包括公共卫生护士在标准产检期间提供的额外指导。如果不包括研究，由于实施和 HPI 成本的增加，混合型计划每位母亲的成本是自我指导型计划的两倍多（140.5 欧元对 56.6 欧元，2022 欧元）。包括研究在内，项目成本分别增加到 190.8 欧元和 106.9 欧元。单向敏感性分析表明了用户数量、应用程序寿命、工资和许可费变化的敏感性：核对表有助于提高成本计算的透明度，并改善未来各项研究之间的比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PharmacoEconomics 医学-药学

CiteScore

8.10

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： PharmacoEconomics is the benchmark journal for peer-reviewed, authoritative and practical articles on the application of pharmacoeconomics and quality-of-life assessment to optimum drug therapy and health outcomes. An invaluable source of applied pharmacoeconomic original research and educational material for the healthcare decision maker. PharmacoEconomics is dedicated to the clear communication of complex pharmacoeconomic issues related to patient care and drug utilization. PharmacoEconomics offers a range of additional features designed to increase the visibility, readership and educational value of the journal’s content. Each article is accompanied by a Key Points summary, giving a time-efficient overview of the content to a wide readership. Articles may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand the scientific content and overall implications of the article.