Proceedings of the 2024 North American Society of Head and Neck Pathology Companion Meeting, Baltimore, MD, March 24, 2024: Navigating Ancillary Studies in Basaloid/Blue Salivary Tumors.

IF 3.2 Q2 PATHOLOGY

Head & Neck Pathology Pub Date : 2024-03-25 DOI:10.1007/s12105-024-01626-5

Kristine S Wong

引用次数: 0

Abstract

Background: Basaloid salivary tumors can demonstrate significant morphologic overlap and be challenging to diagnose.

Methods: A review of select ancillary studies in basaloid salivary tumors was performed.

Results: A number of immunohistochemical stains, including PLAG1, HMGA2, β-catenin, MYB, and RAS Q61R, have been more recently incorporated into the diagnostic workup of basaloid salivary tumors.

Conclusions: Although reported variability in their performance has perhaps limited their widespread adoption, these immunohistochemical studies can nevertheless be useful in supporting pathologic diagnoses, particularly when considered in more specific differentials or when used as a panel with other markers.

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2024 年北美头颈部病理学学会同行会议论文集》，马里兰州巴尔的摩市，2024 年 3 月 24 日：基底样/蓝唾液腺肿瘤辅助研究导航。

背景：基底唾液腺肿瘤可表现出明显的形态学重叠，诊断难度很大：基底唾液腺肿瘤可表现出明显的形态学重叠，诊断具有挑战性：方法：对基底唾液腺肿瘤的部分辅助研究进行回顾：结果：一些免疫组化染色，包括PLAG1、HMGA2、β-catenin、MYB和RAS Q61R，最近已被纳入基底型唾液腺肿瘤的诊断工作中：这些免疫组化研究在支持病理诊断方面还是很有用的，尤其是在考虑更具体的鉴别诊断或与其他标记物一起作为一组标记物使用时。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Head & Neck Pathology PATHOLOGY-

CiteScore

5.70

自引率

9.50%

发文量

期刊介绍： Head & Neck Pathology presents scholarly papers, reviews and symposia that cover the spectrum of human surgical pathology within the anatomic zones of the oral cavity, sinonasal tract, larynx, hypopharynx, salivary gland, ear and temporal bone, and neck. The journal publishes rapid developments in new diagnostic criteria, intraoperative consultation, immunohistochemical studies, molecular techniques, genetic analyses, diagnostic aids, experimental pathology, cytology, radiographic imaging, and application of uniform terminology to allow practitioners to continue to maintain and expand their knowledge in the subspecialty of head and neck pathology. Coverage of practical application to daily clinical practice is supported with proceedings and symposia from international societies and academies devoted to this field. Single-blind peer review The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.