Epidemiological Surveillance of Acute Flaccid Paralysis for Eradication of Poliomyelitis (A Brief Review)

I. Simeonova, I. Mladenova, A. Patel
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Abstract

In May 1988 the World Health Assembly set to World Health Organization (WHO) the goal to achieve a global eradication of poliomyelitis by the year 2000. Surveillance of the acute flaccid paralysis (AFP) remains the ‘gold standard’ for the detection of polio. The criterion of sensitivity of the surveillance system is the incidence from non-polio related AFP, in children under 15 years of age. The aim is to detect more than 1 case of AFP, per 100,000 children. In 2019, WHO announced the eradication of wild poliovirus 3, and poliovirus 2 was eradicated in 2015. Wild poliovirus 1 continues to circulate. The main goals of the WHO Polio Eradication Strategy for the period 2022-2026 are: permanently interrupt all poliovirus transmission in endemic countries (Afghanistan and Pakistan), stop cVDPV (circulating vaccine-derived poliovirus) transmission and prevent outbreaks in non-endemic countries.
为根除脊髓灰质炎对急性弛缓性麻痹进行流行病学监测(简评)
1988 年 5 月,世界卫生大会向世界卫生组织(WHO)提出了到 2000 年在全球根除脊髓灰质炎的目标。对急性弛缓性麻痹(AFP)的监测仍然是检测脊髓灰质炎的 "黄金标准"。监测系统的灵敏度标准是 15 岁以下儿童非脊髓灰质炎相关急性弛缓性麻痹的发病率。目标是在每 10 万名儿童中发现 1 例以上 AFP 病例。2019 年,世卫组织宣布根除脊髓灰质炎野病毒 3,2015 年根除了脊髓灰质炎野病毒 2。野生脊灰病毒 1 仍在流行。世卫组织 2022-2026 年根除脊髓灰质炎战略的主要目标是:永久阻断脊髓灰质炎流行国家(阿富汗和巴基斯坦)的所有脊髓灰质炎病毒传播,阻止 cVDPV(疫苗衍生脊髓灰质炎病毒循环)传播,防止非流行国家爆发脊髓灰质炎。
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