Xiomara Duque Alvarez , Cándido Fernando Alcázar , Ana Hernando Sanz , Isabel Mora Oliver , Laura Granel , José A. Barreras , Alicia Calero , Silvia Carbonell Morote , Carlos Domingo , Rafael Estevan , Israel Oliver , Rafael López Andujar , Luis Sabater , Antonio Compañ , José M. Ramia
{"title":"Tumor sólido pseudopapilar de páncreas: un estudio retrospectivo en la Comunidad Valenciana","authors":"Xiomara Duque Alvarez , Cándido Fernando Alcázar , Ana Hernando Sanz , Isabel Mora Oliver , Laura Granel , José A. Barreras , Alicia Calero , Silvia Carbonell Morote , Carlos Domingo , Rafael Estevan , Israel Oliver , Rafael López Andujar , Luis Sabater , Antonio Compañ , José M. Ramia","doi":"10.1016/j.ciresp.2023.11.015","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Solid pseudopapillary tumors (SPT) of the pancreas are rare exocrine neoplasms of the pancreas. Correct preoperative diagnosis is not always feasible. The treatment of choice is surgical excision. These tumors have a good prognosis with a high disease-free survival rate.</p></div><div><h3>Objective</h3><p>To describe the clinicopathological and radiological characteristics as well as short- and long-term follow-up results of patients who have undergone SPT resection.</p></div><div><h3>Methods</h3><p>Multicenter retrospective observational study in patients with SPT who had undergone surgery from January 2000-January 2022. We have studied preoperative, intraoperative, and postoperative variables as well as the follow-up results (mean 28<!--> <!-->months).</p></div><div><h3>Results</h3><p>Twenty patients with histological diagnosis of SPT in the surgical specimen were included. 90% were women; mean age was 33.5<!--> <!-->years (13-67); 50% were asymptomatic. CT was the most used diagnostic test (90%). The most frequent location was body-tail (60%). Preoperative biopsy was performed in 13 patients (65%), which was correct in 8 patients. Surgeries performed: 7 distal pancreatectomies, 6 pancreaticoduodenectomies, 4 central pancreatectomies, 2 enucleations, and 1 total pancreatectomy. The R0 rate was 95%. Four patients presented major postoperative complications (Clavien-Dindo<!--> <!-->><!--> <!-->II). Mean tumor size was 81<!--> <!-->mm. Only one patient received adjuvant chemotherapy. With a mean follow-up of 28<!--> <!-->months, 5-year disease-free survival was 95%.</p></div><div><h3>Conclusion</h3><p>SPT are large, usually located in the body-tail of the pancreas, and more frequent in women. The R0 rate obtained in our series is very high (95%). The oncological results are excellent.</p></div>","PeriodicalId":50690,"journal":{"name":"Cirugia Espanola","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cirugia Espanola","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0009739X24000356","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
Solid pseudopapillary tumors (SPT) of the pancreas are rare exocrine neoplasms of the pancreas. Correct preoperative diagnosis is not always feasible. The treatment of choice is surgical excision. These tumors have a good prognosis with a high disease-free survival rate.
Objective
To describe the clinicopathological and radiological characteristics as well as short- and long-term follow-up results of patients who have undergone SPT resection.
Methods
Multicenter retrospective observational study in patients with SPT who had undergone surgery from January 2000-January 2022. We have studied preoperative, intraoperative, and postoperative variables as well as the follow-up results (mean 28 months).
Results
Twenty patients with histological diagnosis of SPT in the surgical specimen were included. 90% were women; mean age was 33.5 years (13-67); 50% were asymptomatic. CT was the most used diagnostic test (90%). The most frequent location was body-tail (60%). Preoperative biopsy was performed in 13 patients (65%), which was correct in 8 patients. Surgeries performed: 7 distal pancreatectomies, 6 pancreaticoduodenectomies, 4 central pancreatectomies, 2 enucleations, and 1 total pancreatectomy. The R0 rate was 95%. Four patients presented major postoperative complications (Clavien-Dindo > II). Mean tumor size was 81 mm. Only one patient received adjuvant chemotherapy. With a mean follow-up of 28 months, 5-year disease-free survival was 95%.
Conclusion
SPT are large, usually located in the body-tail of the pancreas, and more frequent in women. The R0 rate obtained in our series is very high (95%). The oncological results are excellent.
期刊介绍:
Cirugía Española, an official body of the Asociación Española de Cirujanos (Spanish Association of Surgeons), will consider original articles, reviews, editorials, special articles, scientific letters, letters to the editor, and medical images for publication; all of these will be submitted to an anonymous external peer review process. There is also the possibility of accepting book reviews of recent publications related to General and Digestive Surgery.