Tumor sólido pseudopapilar de páncreas: un estudio retrospectivo en la Comunidad Valenciana

IF 1.3 4区 医学 Q3 SURGERY
Xiomara Duque Alvarez , Cándido Fernando Alcázar , Ana Hernando Sanz , Isabel Mora Oliver , Laura Granel , José A. Barreras , Alicia Calero , Silvia Carbonell Morote , Carlos Domingo , Rafael Estevan , Israel Oliver , Rafael López Andujar , Luis Sabater , Antonio Compañ , José M. Ramia
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引用次数: 0

Abstract

Introduction

Solid pseudopapillary tumors (SPT) of the pancreas are rare exocrine neoplasms of the pancreas. Correct preoperative diagnosis is not always feasible. The treatment of choice is surgical excision. These tumors have a good prognosis with a high disease-free survival rate.

Objective

To describe the clinicopathological and radiological characteristics as well as short- and long-term follow-up results of patients who have undergone SPT resection.

Methods

Multicenter retrospective observational study in patients with SPT who had undergone surgery from January 2000-January 2022. We have studied preoperative, intraoperative, and postoperative variables as well as the follow-up results (mean 28 months).

Results

Twenty patients with histological diagnosis of SPT in the surgical specimen were included. 90% were women; mean age was 33.5 years (13-67); 50% were asymptomatic. CT was the most used diagnostic test (90%). The most frequent location was body-tail (60%). Preoperative biopsy was performed in 13 patients (65%), which was correct in 8 patients. Surgeries performed: 7 distal pancreatectomies, 6 pancreaticoduodenectomies, 4 central pancreatectomies, 2 enucleations, and 1 total pancreatectomy. The R0 rate was 95%. Four patients presented major postoperative complications (Clavien-Dindo > II). Mean tumor size was 81 mm. Only one patient received adjuvant chemotherapy. With a mean follow-up of 28 months, 5-year disease-free survival was 95%.

Conclusion

SPT are large, usually located in the body-tail of the pancreas, and more frequent in women. The R0 rate obtained in our series is very high (95%). The oncological results are excellent.

Abstract Image

胰腺实性假乳头状瘤:巴伦西亚社区的一项回顾性研究
导言胰腺实性假乳头状瘤(SPT)是一种罕见的胰腺外分泌肿瘤。正确的术前诊断并不总是可行的。首选治疗方法是手术切除。方法对 2000 年 1 月至 2022 年 1 月期间接受手术的 SPT 患者进行多中心回顾性观察研究。我们对术前、术中和术后变量以及随访结果(平均 28 个月)进行了研究。结果纳入了 20 例手术标本组织学诊断为 SPT 的患者。90%为女性;平均年龄为33.5岁(13-67岁);50%无症状。CT 是最常用的诊断测试(90%)。最常见的位置是体尾(60%)。13名患者(65%)进行了术前活检,其中8名患者的活检结果是正确的。手术情况7例远端胰腺切除术、6例胰十二指肠切除术、4例中央胰腺切除术、2例胰腺切除术和1例全胰腺切除术。R0率为95%。四名患者出现了严重的术后并发症(Clavien-Dindo II)。肿瘤平均大小为 81 毫米。只有一名患者接受了辅助化疗。平均随访时间为28个月,5年无病生存率为95%。在我们的系列研究中,R0 率非常高(95%)。肿瘤治疗效果极佳。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cirugia Espanola
Cirugia Espanola SURGERY-
CiteScore
1.20
自引率
21.10%
发文量
173
审稿时长
53 days
期刊介绍: Cirugía Española, an official body of the Asociación Española de Cirujanos (Spanish Association of Surgeons), will consider original articles, reviews, editorials, special articles, scientific letters, letters to the editor, and medical images for publication; all of these will be submitted to an anonymous external peer review process. There is also the possibility of accepting book reviews of recent publications related to General and Digestive Surgery.
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