Restricted spatial models for the analysis of geographic and racial disparities in the incidence of low birthweight in Pennsylvania

IF 2.1 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Guangzi Song , Loni Philip Tabb , Harrison Quick
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Abstract

The incidence of low birthweight is a common measure of public health due to the increased risk of complications associated with infants having low and very low birthweights. Moreover, many factors that increase the risk of an infant having a low birthweight can be linked to the mother’s socioeconomic status, leading to large racial/ethnic disparities in its incidence. Our objective is thus to analyze the incidence of low and very low birthweight in Pennsylvania counties by race/ethnicity. Due to the small number of births in many Pennsylvania counties when stratified by race/ethnicity, our methods must walk a fine line: While we wish to leverage spatial structure to improve the precision of our estimates, we also wish to avoid oversmoothing the data, which can yield spurious conclusions. As such, we develop a framework by which we can measure (and control) the informativeness of our spatial model. To analyze the data, we first model the Pennsylvania birth data using the conditional autoregressive model to demonstrate the extent to which it can lead to oversmoothing. We then reanalyze the data using our proposed framework and highlight its ability to detect (or not detect) evidence of racial/ethnic disparities in the incidence of low birthweight.

用于分析宾夕法尼亚州出生体重不足发生率的地域和种族差异的限制性空间模型
出生体重过轻是衡量公共卫生的一个常见指标,因为出生体重过轻或过轻的婴儿出现并发症的风险增加。此外,许多增加婴儿出生体重不足风险的因素都与母亲的社会经济地位有关,从而导致婴儿出生体重不足的发生率存在巨大的种族/民族差异。因此,我们的目标是按种族/族裔分析宾夕法尼亚州各县低出生体重和超低出生体重的发生率。由于宾夕法尼亚州许多县按种族/族裔分层时的出生人数较少,我们的方法必须小心谨慎:虽然我们希望利用空间结构来提高估算的精确度,但我们也希望避免对数据进行过度平滑,因为过度平滑会产生虚假的结论。因此,我们开发了一个框架,通过该框架,我们可以衡量(并控制)空间模型的信息量。为了分析数据,我们首先使用条件自回归模型对宾夕法尼亚州的出生数据进行建模,以证明该模型可能导致的超平滑程度。然后,我们使用我们提出的框架对数据进行重新分析,并强调其检测(或不检测)出生体重不足发生率中种族/民族差异证据的能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Spatial and Spatio-Temporal Epidemiology
Spatial and Spatio-Temporal Epidemiology PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
5.10
自引率
8.80%
发文量
63
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