2022 TB programme review in Pakistan: strengthening governance, with better patient diagnosis and treatment

M. van den Boom, K. Bennani, C. Sismanidis, C. Gunneberg, L. Khawaja, M.A. Safdar, C. Muhwa, E. Heldal, D.M. Cirillo, A.W. Khan, R. Fatima, B.J. Khan, S. Tahseen, M.G. ElMedrek, Y. Hutin
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Abstract

BACKGROUNDIn Pakistan, 84% of healthcare is provided by the private sector. We conducted an epidemiological and programme review for TB to document progress and guide further efforts.METHODSSurveillance and data systems were assessed before analysing epidemiological data. We reviewed the programme at federal, provincial and peripheral levels and compiled national data along with WHO estimates to describe the evolution of epidemiological and programme indicators.RESULTSIn 2021, of the estimated number of TB cases, 55% of overall cases and 18% of drug-resistant cases were diagnosed and treated respectively. The contribution of the private sector in case detection increased from 30% in 2017 to 40% by 2021. For newly diagnosed pulmonary TB cases, the overall proportion of confirmed cases was 52%. In 2021, testing for rifampicin resistance among confirmed cases was 66% for new and 84% for previously treated patients. The treatment success rate exceeded 90% for drug susceptible TB. The main challenges identified were a funding gap (60% in 2021–2023), fragmented electronic systems for data collection and suboptimal coordination among provinces.CONCLUSIONSThe main challenges prevent further progress in controlling TB. By addressing these, Pakistan could improve coverage of interventions, including diagnosis and treatment. Bacteriological confirmation using recommended diagnostics also requires further optimisation.
2022 年巴基斯坦结核病计划审查:加强治理,改善患者诊断和治疗
背景在巴基斯坦,84% 的医疗服务由私营部门提供。在分析流行病学数据之前,我们对监测和数据系统进行了评估。我们对联邦、省和周边地区的计划进行了审查,并汇编了全国数据和世界卫生组织的估计数据,以描述流行病学和计划指标的演变情况。结果 2021 年,在估计的结核病例数中,55% 的总病例和 18% 的耐药病例分别得到了诊断和治疗。私营部门对病例发现的贡献率从 2017 年的 30% 提高到 2021 年的 40%。在新诊断的肺结核病例中,确诊病例的总体比例为 52%。2021 年,新确诊病例中利福平耐药性检测率为 66%,既往接受过治疗的患者中利福平耐药性检测率为 84%。易服药结核病的治疗成功率超过 90%。已确定的主要挑战是资金缺口(2021-2023 年为 60%)、零散的数据收集电子系统以及各省之间协调不佳。通过应对这些挑战,巴基斯坦可以提高包括诊断和治疗在内的干预措施的覆盖率。使用推荐诊断方法进行细菌学确认也需要进一步优化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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