Detección de anticuerpos contra el VHC y los factores de riesgo en la población con acceso a la seguridad social en México

IF 1.5 Q3 GASTROENTEROLOGY & HEPATOLOGY
{"title":"Detección de anticuerpos contra el VHC y los factores de riesgo en la población con acceso a la seguridad social en México","authors":"","doi":"10.1016/j.rgmx.2024.01.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction and aim</h3><p>Timely detection and diagnosis of hepatitis C virus (HCV) involves identifying the population that is predisposed to treatment and prevention, thus limiting complications and preventing infection. The aim of this study was to analyze and describe risk factors associated with anti-HCV antibody detection in a population with access to public healthcare that participated in a national screening program.</p></div><div><h3>Material and methods</h3><p>An analytic cross-sectional study was conducted that utilized data related to rapid tests carried out between September 2021 and October 2022 in 26 of the 32 states of Mexico. Anti-HCV reactive tests were selected, according to age and sex, for analyzing and comparing possible risk factors through descriptive and inferential statistics. The geographic distribution and density of the screening program at the state and municipal levels was analyzed.</p></div><div><h3>Results</h3><p>There were 75,185 anti-HCV antibody detections, 2,052 reactive tests, and mean participant age was 44.3 years (±15.1). Occupation: 32.3% were employees, 19% were housewives, and 18.2% were healthcare workers. Five out of every 10 cases had no indication of risk factors, but there was a 1.4 and 5-times greater likelihood of anti-HCV detection in men with a history of sharps injury or intravenous psychoactive substance use, compared with women. Regarding place of residence, 80% of the reactive tests were concentrated in the State of Mexico, Mexico City, and Guanajuato.</p></div><div><h3>Conclusions</h3><p>The evidence herein helps determine the population and risk factors that should be focused on in carrying out the HCV microelimination strategy of continuous screening, diagnosis, medical treatment access, and epidemiologic surveillance.</p></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0375090624000132/pdfft?md5=abb90a025b1c1aa09cc020d1214634d0&pid=1-s2.0-S0375090624000132-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de Gastroenterologia de Mexico","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0375090624000132","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction and aim

Timely detection and diagnosis of hepatitis C virus (HCV) involves identifying the population that is predisposed to treatment and prevention, thus limiting complications and preventing infection. The aim of this study was to analyze and describe risk factors associated with anti-HCV antibody detection in a population with access to public healthcare that participated in a national screening program.

Material and methods

An analytic cross-sectional study was conducted that utilized data related to rapid tests carried out between September 2021 and October 2022 in 26 of the 32 states of Mexico. Anti-HCV reactive tests were selected, according to age and sex, for analyzing and comparing possible risk factors through descriptive and inferential statistics. The geographic distribution and density of the screening program at the state and municipal levels was analyzed.

Results

There were 75,185 anti-HCV antibody detections, 2,052 reactive tests, and mean participant age was 44.3 years (±15.1). Occupation: 32.3% were employees, 19% were housewives, and 18.2% were healthcare workers. Five out of every 10 cases had no indication of risk factors, but there was a 1.4 and 5-times greater likelihood of anti-HCV detection in men with a history of sharps injury or intravenous psychoactive substance use, compared with women. Regarding place of residence, 80% of the reactive tests were concentrated in the State of Mexico, Mexico City, and Guanajuato.

Conclusions

The evidence herein helps determine the population and risk factors that should be focused on in carrying out the HCV microelimination strategy of continuous screening, diagnosis, medical treatment access, and epidemiologic surveillance.

墨西哥享受社会保障人群中的丙型肝炎病毒抗体检测和风险因素。
导言和目的及时发现和诊断丙型肝炎病毒(HCV)涉及到确定有治疗和预防倾向的人群,从而限制并发症和预防感染。本研究旨在分析和描述在参与国家筛查计划、可获得公共医疗保健服务的人群中,与抗-HCV 抗体检测相关的风险因素。材料和方法本研究利用 2021 年 9 月至 2022 年 10 月期间在墨西哥 32 个州中的 26 个州进行的快速检测相关数据,开展了一项横断面分析研究。根据年龄和性别选择抗-HCV 反应性检测,通过描述性和推论性统计分析和比较可能的风险因素。结果共检测出 75,185 例抗-HCV 抗体,2,052 例反应性检测,参与者平均年龄为 44.3 岁(±15.1)。职业32.3%为雇员,19%为家庭主妇,18.2%为医护人员。每 10 个病例中就有 5 个没有显示风险因素,但与女性相比,有利器伤害史或静脉注射精神活性物质史的男性检出抗-HCV 的可能性分别高出 1.4 倍和 5 倍。在居住地方面,80% 的反应性检测结果集中在墨西哥州、墨西哥城和瓜纳华托州。结论本报告中的证据有助于确定在实施持续筛查、诊断、就医和流行病学监测的 HCV 微消除策略时应重点关注的人群和风险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Revista de Gastroenterologia de Mexico
Revista de Gastroenterologia de Mexico GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
1.60
自引率
12.50%
发文量
102
审稿时长
12 weeks
期刊介绍: La Revista de Gastroenterología de México es el órgano oficial de la Asociación Mexicana de Gastroenterología. Sus espacios están abiertos a los miembros de la Asociación como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos, cumpliendo con las políticas editoriales que a continuación se mencionan. El objetivo principal de la Revista de Gastroenterología de México, es publicar trabajos originales del amplio campo de la gastroenterología, así como proporcionar información actualizada y relevante para el área de la especialidad y áreas afines. Los trabajos científicos incluyen las áreas de Gastroenterología clínica, endoscópica, quirúrgica y pediátrica.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信