The Relationship between Diabetes Mellitus with Senile Cataracts

Muhammad Shaifullah, Nur Khoma Fatmawati, Sjarif Ismail
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Abstract

A cataract is any condition of cloudiness of the eye lens (lens opacity) caused by denaturation of lens proteins, lens hydration, or both. Senile cataract refers to cataracts suffered by patients aged > 50 years. Cataract is a multifactorial disease. About 90% of cataract incidence is related to age. Other factors such as radiation exposure, trauma, medicine, or the presence of systemic disorders are also involved in diabetes melitus. The study’s goal was to analyze the relationship between diabetes mellitus and the incidence of senile cataract. The research was carried out using an analytical observational method and utilized a case-control study approach with individual matching. The data was taken from the medical record installation at the Eye Clinic of SMEC Samarinda with a purposive sampling method. The sample in this study included patients with eye disorders or diseases.The patients with a cataract diagnosis were involved as the case group, while non-cataract patients as the control group. All patients were received treatment at the SMEC Samarinda Eye Clinic in the period January to December 2021 and already met the research sample criteria. The data then tested using the Chi-Square test with a significance value of p <0.05, which was considered significant. A total of 334 samples were obtained, consisting of 167 case samples and 167 control samples. The results indicated that there was a relationship between diabetes mellitus and senile cataract (p = 0.000) with an odds ratio (OR) value of 3.150. It can be concluded that diabetes mellitus had a relationship with the incidence of senile cataract, since patients with diabetes mellitus were 3.150 times more at risk of suffering senile cataracts than non-diabetics patients.
糖尿病与老年性白内障的关系
白内障是指由于晶状体蛋白质变性、晶状体水化或两者共同作用而导致的眼球晶状体混浊(晶状体不透明)。老年性白内障是指年龄大于 50 岁的白内障患者。白内障是一种多因素疾病。约 90% 的白内障发病率与年龄有关。其他因素,如辐射照射、外伤、药物或全身性疾病的存在,也与白内障有关。这项研究的目的是分析糖尿病与老年性白内障发病率之间的关系。研究采用分析观察法,并利用个体匹配的病例对照研究方法。数据来自萨马林达 SMEC 眼科医院的医疗记录,采用有目的的抽样方法。白内障患者为病例组,非白内障患者为对照组。所有患者均于 2021 年 1 月至 12 月期间在 SMEC 萨马林达眼科诊所接受治疗,并符合研究样本标准。然后,数据采用Chi-Square检验法进行检验,显著性检验值为P<0.05,即认为数据具有显著性。共获得 334 个样本,包括 167 个病例样本和 167 个对照样本。结果表明,糖尿病与老年性白内障之间存在关系(P = 0.000),几率比(OR)值为 3.150。由此可以得出结论,糖尿病与老年性白内障的发病率有一定关系,因为糖尿病患者患老年性白内障的风险是非糖尿病患者的 3.150 倍。
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